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    Mouse Anti-H3C1 Recombinant Antibody (clone 3B12) (CAT#: VS7-0425-WR40)

    This product is a mouse IgG recombinant antibody that binds to human H3C1. The antibody 3B12 can be used for WB and IP assays. It also cross-reacts with rat and mouse.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Glial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_B_7_5.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_8_3.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_7_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_9_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Elongated or late spermatids
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Leydig cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Pachytene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Peritubular cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Preleptotene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Round or early spermatids
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Sertoli cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_4_6.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/42570/103608_A_8_8.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (U-2 OS)
    Figure 7 RNA cell line category: Cell line enhanced (U-2 OS)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000275714-H3C1

    Specifications

    • Immunogen
    • Synthetic Histone H3 (Di Methyl Lys27) peptide
    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • Human H3C1
    • Species Reactivity
    • Human, Mouse, Rat
    • Clone
    • 3B12
    • Molecule Class
    • Structure Molecule
    • Applications
    • WB, IP
    • Conjugate
    • Unconjugated
    • Related Disease
    • Glioma (GLM)

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Format
    • Liquid
    • Concentration
    • 1 mg/mL
    • Buffer
    • PBS, pH 7.4
    • Preservative
    • 0.02% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:1000 - 1:3000
      Immunoprecipitation: 1:200

    Target

    • Alternative Names
    • H3/A; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3C10; H3C11; H3C12; HIST1H3A
    • Long Name
    • H3 clustered histone 1
    • Cellular Localization
    • Chromosome; Nucleosome core; Nucleus
    • Post Translation Modifications
    • Acetylation; ADP-ribosylation; Citrullination; Hydroxylation; Lipoprotein; Methylation; Phosphoprotein; Ubl conjugation
    • Function
    • DNA-binding

    Recommended Products

    Isotype Control

    Secondary Antibody

    Reconstitution Buffer

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "H3C1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products
    CAT Product Name Application Type
    VS3-FY648 Recombinant Rabbit Anti-HIST1H3A Antibody (clone R08-4A0) WB, IHC-Fr, IHC-P, ICC, IF, IP, ChIP Rabbit IgG
    VS3-FY649 Recombinant Rabbit Anti-HIST1H3A (phospho Ser10/Thr11) Antibody (clone R08-6C4) WB, IHC-Fr, IHC-P, ICC, IF, IP Rabbit IgG
    VS3-FY650 Recombinant Rabbit Anti-HIST1H3A (phospho Thr3) Antibody (clone R08-9D6) WB, ICC, IF Rabbit IgG
    VS3-WK2176 Rabbit Anti-H3C1 (pS10) Recombinant Antibody (clone BP6092) IHC-P Rabbit IgG
    VS3-WK2196 Rabbit Anti-H3C1 (acetyl K14) Recombinant Antibody (clone R06-2F5) WB, ICC, IF, IP Rabbit IgG

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