Recombinant Human Anti-H7N9 HA Antibody (L4A-14) (CAT#: PABC-357)

This product is a recombinant Human antibody that can recognize H7N9 HA. L4A-14, bound into the sialic acid binding site and made contacts with haemagglutinin residues that were conserved in the great majority of 2016-2017 H7N9 isolates.


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Neut

Figure 1 Human Anti-H7N9 HA Antibody (L4A-14) in Neut.

Figure 1 Human Anti-H7N9 HA Antibody (L4A-14) in Neut.

Protection against lethal infection with H7N9 in mice by antibodies a,b, In vivo prophylactic and therapeutic effects of neutralizing antibodies L4A-14, L3A-44 and L4B-18 against high pathogenic H7N9 A/Guangdong/TH005/2017 (an HP avian virus related to A/Guangdong/17SF003/2016) infection in BALB/c mice (n = 5 per group).

Huang, K. Y. A., Rijal, P., Jiang, H., Wang, B., Schimanski, L., Dong, T., ... & Townsend, A. R. (2019). Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nature microbiology, 4(2), 306-315.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • H7N9 HA
  • Species Reactivity
  • Influenza A virus H7N9
  • Clone
  • L4A-14
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • H7N9 HA; Influenza A virus H7N9 Hemagglutinin

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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