Chicken Anti-HARS Recombinant Antibody (clone 4B1); Fab Fragment
CAT#: FAMAB-0005JF-F(E)
Recombinant chicken monoclonal antibody specially binds to human histidyl tRNA synthetase (HARS). This anti-HARS antibody 4B1 can be potentially wildly used in the treatment of Poly-myositis.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human skin
Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170445-HARS
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Specifications
- Immunogen
- Antigen mixture 1 (annexin XI, centromere protein B, DNA topoisomerase I, histidyl tRNA synthetase, Ro60, Rpp38 and U1A) and mixture 2 (a-fodrin, human Pop1 protein, heat shock protein B3, Ro52, Rpp30, Rrp4 and Rrp42)
- Host Species
- Chicken
- Derivation
- Chicken phage display scFv library
- Type
- Chicken Fab
- Specificity
- Human HARS
- Species Reactivity
- Human
- Clone
- 4B1
- Applications
- IB, WB, ELISA, FuncS
- Related Disease
- Poly-myositis
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 4B1"
- CAT
- Product Name
See other products for "HARS"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2392z | Mouse Anti-HARS Recombinant Antibody (clone 40C3) | WB, FC, ICC, IP, Dot | Mouse IgG1 |
| HPAB-N0349-YC | Human Anti-HARS Recombinant Antibody (clone KL31-478) | ELISA, FC | Human IgG1, κ |
| HPAB-N0350-YC | Human Anti-HARS Recombinant Antibody (clone KL31-240) | ELISA, FC | Human IgG4, κ |
| FAMAB-0005JF | Chicken Anti-HARS Recombinant Antibody (clone 4B1) | IB, WB, ELISA, FuncS | |
| ZG-445C | Human Anti-HARS Recombinant Antibody (ZG-445C) | ELISA | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1564 | Rabbit Anti-HARS Recombinant Antibody (clone DS1564AB) | WB, IHC-P, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0349-YC-S(P) | Human Anti-HARS Recombinant Antibody (clone KL31-478); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-N0350-YC-S(P) | Human Anti-HARS Recombinant Antibody (clone KL31-240); scFv Fragment | ELISA, FC | Human scFv |
| FAMAB-0005JF-S(P) | Chicken Anti-HARS Recombinant Antibody (clone 4B1); scFv Fragment | IB, WB, ELISA, FuncS | Chicken scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0349-YC-F(E) | Human Anti-HARS Recombinant Antibody (clone KL31-478); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-N0350-YC-F(E) | Human Anti-HARS Recombinant Antibody (clone KL31-240); Fab Fragment | ELISA, FC | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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