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Chicken Anti-HARS Recombinant Antibody (clone 4B1); Fab Fragment (CAT#: FAMAB-0005JF-F(E))

Recombinant chicken monoclonal antibody specially binds to human histidyl tRNA synthetase (HARS). This anti-HARS antibody 4B1 can be potentially wildly used in the treatment of Poly-myositis.


See more Engineered Antibody products for HARS
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  • Datasheet
  • MSDS
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Normal Tissue
Figure 1 IHC staining of human skin
Figure 1 IHC staining of human skin
(Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/ihc_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_8_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_9_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_5_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170445-HARS

Specifications

  • Immunogen
  • Antigen mixture 1 (annexin XI, centromere protein B, DNA topoisomerase I, histidyl tRNA synthetase, Ro60, Rpp38 and U1A) and mixture 2 (a-fodrin, human Pop1 protein, heat shock protein B3, Ro52, Rpp30, Rrp4 and Rrp42)
  • Host Species
  • Chicken
  • Derivation
  • Chicken phage display scFv library
  • Type
  • Chicken Fab
  • Specificity
  • Human HARS
  • Species Reactivity
  • Human
  • Clone
  • 4B1
  • Applications
  • IB, WB, ELISA, FuncS
  • Related Disease
  • Poly-myositis

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • HRS; CMT2W; USH3B; Jo-1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 4B1"

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Recombinant Antibody

CAT Product Name Application Type
MOB-2392z Mouse Anti-HARS Recombinant Antibody (clone 40C3) WB, FC, ICC, IP, Dot Mouse IgG1
MOB-2302MZ Recombinant Mouse Anti-Human HARS Antibody WB Mouse antibody
HPAB-N0349-YC Human Anti-HARS Recombinant Antibody (clone KL31-478) ELISA, FC Human IgG1, κ
HPAB-N0350-YC Human Anti-HARS Recombinant Antibody (clone KL31-240) ELISA, FC Human IgG4, κ
VS3-QX498 Mouse Anti-HARS Recombinant Antibody (clone 4H5-D9-D4) WB Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1564 Rabbit Anti-HARS Recombinant Antibody (clone DS1564AB) WB, IHC-P, IP Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-N0349-YC-S(P) Human Anti-HARS Recombinant Antibody (clone KL31-478); scFv Fragment ELISA, FC Human scFv
HPAB-N0350-YC-S(P) Human Anti-HARS Recombinant Antibody (clone KL31-240); scFv Fragment ELISA, FC Human scFv
FAMAB-0005JF-S(P) Chicken Anti-HARS Recombinant Antibody (clone 4B1); scFv Fragment IB, WB, ELISA, FuncS Chicken scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-N0349-YC-F(E) Human Anti-HARS Recombinant Antibody (clone KL31-478); Fab Fragment ELISA, FC Human Fab
HPAB-N0350-YC-F(E) Human Anti-HARS Recombinant Antibody (clone KL31-240); Fab Fragment ELISA, FC Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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