Human Anti-HARS Recombinant Antibody (clone KL31-478) (CAT#: HPAB-N0349-YC)
Provided are antibodies that specifically bind to human histidyl-tRNA synthetase. The antibody can be used for treating cancer, including as standalone therapies or in combination with cancer immunotherapies, for example, immune checkpoint modulators such as PD-1 inhibitors.
Specific Inquiry
FC
Figure 1 show that anti-HRS antibodies from the KL31 series blocked binding of Fc-HRS(2-60) to NRP2 in a concentration-dependent manner, whereas other antibodies of the AB04 and AB13 series did not demonstrate significant blocking characteristics in this assay.
Fig.A shows control human IgG1 (filled circles), KL31-467 (filled triangles), KL31-356 (partially filled triangles), mouse clone 13C8 (crosses), and Fig.B shows control human IgG1 (filled circles), AB04-425 (open triangles), AB13-288 (partially filled squares), and KL31-478 (filled triangles), which are shown as the percentage of streptavidinPE+/NRP2+ cells in the viable singlet gate.
Specifications
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- Human HARS
- Species Reactivity
- Human, Cynomolgus
- Clone
- KL31-478
- Applications
- ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry. Please see the Published Data for further information.
Target
- Alternative Names
- Histidyl-TRNA Synthetase; EC 6.1.1.21; HisRS; HRS; Histidine TRNA Ligase 1, Cytoplasmic; Histidine--TRNA Ligase, Cytoplasmic
- Gene ID
- 3035
- UniProt ID
- P12081
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone KL31-478"
See other products for "HARS"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2302MZ | Recombinant Mouse Anti-Human HARS Antibody | WB | Mouse antibody |
| FAMAB-0005JF | Chicken Anti-HARS Recombinant Antibody (clone 4B1) | IB, WB, ELISA, FuncS | |
| ZG-445C | Human Anti-HARS Recombinant Antibody (ZG-445C) | ELISA | Human IgG1, κ |
| VS3-QX498 | Mouse Anti-HARS Recombinant Antibody (clone 4H5-D9-D4) | WB | Mouse IgG1 |
| VS3-FY2731 | Mouse Anti-HARS Recombinant Antibody (VS3-FY2731) | WB | Mouse IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-N0349-YC. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
-1.jpg)
Application: WB, ELISA, FC, IHC, IP
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
