Human Anti-HARS Recombinant Antibody (clone KL31-478) (CAT#: HPAB-N0349-YC)
Provided are antibodies that specifically bind to human histidyl-tRNA synthetase. The antibody can be used for treating cancer, including as standalone therapies or in combination with cancer immunotherapies, for example, immune checkpoint modulators such as PD-1 inhibitors.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 show that anti-HRS antibodies from the KL31 series blocked binding of Fc-HRS(2-60) to NRP2 in a concentration-dependent manner, whereas other antibodies of the AB04 and AB13 series did not demonstrate significant blocking characteristics in this assay.
Fig.A shows control human IgG1 (filled circles), KL31-467 (filled triangles), KL31-356 (partially filled triangles), mouse clone 13C8 (crosses), and Fig.B shows control human IgG1 (filled circles), AB04-425 (open triangles), AB13-288 (partially filled squares), and KL31-478 (filled triangles), which are shown as the percentage of streptavidinPE+/NRP2+ cells in the viable singlet gate.
Specifications
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- Human HARS
- Species Reactivity
- Human, Cynomolgus
- Clone
- KL31-478
- Applications
- ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry. Please see the Published Data for further information.
Target
- Alternative Names
- Histidyl-TRNA Synthetase; EC 6.1.1.21; HisRS; HRS; Histidine TRNA Ligase 1, Cytoplasmic; Histidine--TRNA Ligase, Cytoplasmic
- Gene ID
- 3035
- UniProt ID
- P12081
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone KL31-478"
See other products for "HARS"
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2392z | Mouse Anti-HARS Recombinant Antibody (clone 40C3) | WB, FC, ICC, IP, Dot | Mouse IgG1 |
MOB-2302MZ | Recombinant Mouse Anti-Human HARS Antibody | WB | Mouse antibody |
HPAB-N0350-YC | Human Anti-HARS Recombinant Antibody (clone KL31-240) | ELISA, FC | Human IgG4, κ |
FAMAB-0005JF | Chicken Anti-HARS Recombinant Antibody (clone 4B1) | IB, WB, ELISA, FuncS | |
VS3-QX498 | Mouse Anti-HARS Recombinant Antibody (clone 4H5-D9-D4) | WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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