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    Mouse Anti-HARS Recombinant Antibody (VS3-FY2731) (CAT#: VS3-FY2731)

    The anti-HARS antibody is a mouse recombinant monoclonal antibody that is designed to selectively bind to human HARS protein. It exhibits cross-reactivity with mouse, monkey. This monoclonal antibody is potential for conducting research on disease research of Charcot-Marie-Tooth Disease, Axonal, Type 2W and Usher Syndrome, Type Iiib. Its utility extends to application: Western Blot assay.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human skin
    Figure 1 IHC staining of human skin
    (Immunohistochemical staining of human skin shows strong cytoplasmic positivity in epidermal cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/ihc_selected.jpg
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_8_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_9_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_5_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/36539/75988_A_9_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170445-HARS

    Specifications

    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • Histidyl-TRNA Synthetase of human, mouse and monkey origins
    • Species Reactivity
    • Human, Mouse, Monkey
    • Applications
    • WB
    • Conjugate
    • Unconjugated, FITC
    • Related Disease
    • Charcot-Marie-Tooth Disease, Axonal, Type 2W and Usher Syndrome, Type Iiib

    Product Property

    • Clonality
    • Monoclonal Antibody
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • Western Blot: 1/500-1/1000

    Target

    • Alternative Names
    • Histidyl-TRNA Synthetase; EC 6.1.1.21; HisRS; HRS; Histidine TRNA Ligase 1, Cytoplasmic; Histidine--TRNA Ligase, Cytoplasmic
    • Sequence Similarities
    • Belongs to the class-II aminoacyl-tRNA synthetase family.
    • Cellular Localization
    • Cytoplasm
    • Post Translation Modifications
    • Ubiquitination at Lys75 and Lys230
      Modification sites at PhosphoSitePlus
      Glycosylation from GlyGen 1 site, 1 O-linked glycan (1 site)
    • Function
    • Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP) (PubMed:29235198).
      Plays a role in axon guidance.

    Recommended Products

    Secondary Antibody

    Isotype Control

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "HARS"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products
    CAT Product Name Application Type
    MOB-2392z Mouse Anti-HARS Recombinant Antibody (clone 40C3) WB, FC, ICC, IP, Dot Mouse IgG1
    HPAB-N0349-YC Human Anti-HARS Recombinant Antibody (clone KL31-478) ELISA, FC Human IgG1, κ
    HPAB-N0350-YC Human Anti-HARS Recombinant Antibody (clone KL31-240) ELISA, FC Human IgG4, κ
    FAMAB-0005JF Chicken Anti-HARS Recombinant Antibody (clone 4B1) IB, WB, ELISA, FuncS
    VS3-QX498 Mouse Anti-HARS Recombinant Antibody (clone 4H5-D9-D4) WB Mouse IgG1

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