Recombinant Human Anti-HBV Antibody (C9G9) (CAT#: HPAB-0002-WJ)

This product is a human monoclonal IgG kappa antibody targeting human hepatitis B surface antigen. Antibody C9G9 can effectively block the HBV replication in vitro, and therefore has a good ability to neutralize the hepatitis B virus, as prevention of HBV infection drugs.

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Neut

Figure 1 HBV-neutralizing activity of the bispecific antibodies.

(D) The binding of C1G1 and 2B5F5 to HBsAg was markedly reduced when HBsAg was preincubated with C4D2-BsAb but not with C4G4 plus D2H2. C4G4 plus D2H2, or C4D2-BsAb was first incubated with biotinHBsAg. The mixtures were then transferred to the plates coated with anti-HBsAg antibodies A3E3, A6E6, B7F7, C1G1, C9G9, D10H10, 2B5F5, 2C7G7, 2D4H4 and 2D5H5. After 2 h incubation, the plates were washed and biotin-HBsAg bound were detected with HRP-strepavidin conjugated. Results were shown as mean ± SD of three independent experiments.

Tan, W., Meng, Y., Li, H., Chen, Y., Han, S., Zeng, J., ... & Guo, Y. (2013, November). A bispecific antibody against two different epitopes on hepatitis B surface antigen has potent hepatitis B virus neutralizing activity. In MAbs (Vol. 5, No. 6, pp. 946-955). Taylor & Francis.


Specifications

  • Host Species
  • Human
  • Derivation
  • Hepatitis B vaccination isolated PBMCs peripheral blood
  • Type
  • Human IgG
  • Specificity
  • Holistic hepatitis B surface protein
  • Species Reactivity
  • Hepatitis B virus
  • Clone
  • C9G9
  • Applications
  • Neut
  • Related Disease
  • HBV (hepatitis B virus) infection

Applications

  • Application Notes
  • The HBV antibody has been reported in applications of Neutralization.

Target

  • Alternative Names
  • HBV; Holistic hepatitis B surface protein; Hepatitis B virus

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "HBV"


For research use only. Not intended for any clinical use.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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