Recombinant Anti-HCMV gB (AD-1 x AD-2) Biparatopic Antibody, Tandem scFv (Clone SM1-6 x Clone 2F10)
CAT#: VS-0525-YC90
The Recombinant Anti-HCMV gB (AD-1 x AD-2) Biparatopic Antibody, Tandem scFv (Clone SM1-6 x Clone 2F10) functions as a biparatopic antibody (bpAb), recognizing two separate HCMV gB epitopes. Its tandem scFv construction involves the SM1-6 scFv (targeting Antigenic domain 1, AD-1) N-terminally fused to the 2F10 scFv (specific for Antigenic domain 2, AD-2: SHRANETIYNTTLKYGDTTGTNTTK).
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- HCMV gB
- Species Reactivity
- HCMV
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- SM1-6
- Clone 2
- 2F10
- Epitope 1
- Antigenic domain 1 (AD-1)
- Epitope 2
- Antigenic domain 2 (AD-2), SHRANETIYNTTLKYGDTTGTNTTK
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Human cytomegalovirus (HCMV) glycoprotein gB
Target
- Introduction
- Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. It is also known as human herpesvirus-5 (HHV-5). Within Herpesviridae, HCMV belongs to the Betaherpesvirinae subfamily, which also includes cytomegaloviruses from other mammals. Envelope glycoprotein forms spikes at the surface of virion envelope. It is essential for the initial attachment to heparan sulfate moities of the host cell surface proteoglycans.
- Alternative Names
- Human Cytomegalovirus; HCMV; Human Cytomegalovirus envelope glycoprotein B; HCMV gB
- Gene ID
- 3077424
- UniProt ID
- F5HB53
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Datasheet
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