Human Anti-HCMV gB Recombinant Antibody (clone 1G2)
CAT#: FAMAB-0143JF
This is a human IgG3-lambda antibody specially binds to domain I of glycoprotein B (gB) of human cytomegalovirus (HCMV). Clone 1G2 has a reactivity with domain I peptide (aa 132-344) and has a 50% neutralization at concentrations of 0.2-1.3 mg/ml.
Published Data
IHC
Figure 1 EM two-dimensional class averages of gB-698glyco (top panels) and gB-698glyco in complex with 1G2 Fab.
Each value represents the mean ± S.E.M. of duplicate measurements from at least four independent experiments.
Chandramouli, S., Ciferri, C., Nikitin, P. A., Caló, S., Gerrein, R., Balabanis, K., ... & Carfi, A. (2015). Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody. Nature communications, 6(1), 1-12.
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Specifications
- Host Species
- Human
- Type
- Human IgG3, λ
- Specificity
- HCMV gB
- Species Reactivity
- HCMV
- Clone
- 1G2
- Applications
- WB, FC, IHC
- Related Disease
- HCMV infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HCMV gB antibody has been reported in applications of Western Blot, Flow Cytometry, Immunohistochemistry.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-443-S(P) | Recombinant Anti-HCMV GB Antibody scFv Fragment | WB, Neut, FuncS | scFv |
| HPAB-0639-CN-S(P) | Recombinant Human Anti-HCMV gB Antibody scFv Fragment (2F10) | ELISA, Neut | Human scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-443 | Recombinant Human Anti-HCMV GB Antibody | FC, Neut, Funcs | IgG |
| FAMAB-0173CQ | Recombinant Mouse Anti-HCMV gB Antibody (7-17) | ELISA, Neut | Mouse IgG3, κ |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1032LC | Anti-HCMV gB Recombinant Antibody (TI-23) | ELISA | Humanized antibody |
| MRO-1032LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (TI-23) | ELISA | Humanized antibody |
| MRO-1032LC-F(E) | Anti-HCMV gB Recombinant Antibody Fab Fragment (TI-23) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
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| MRO-1033LC-S(P) | Anti-HCMV gB Recombinant Antibody scFv Fragment (C1) | ELISA | Human antibody |
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| CAT | Product Name | Application | Type |
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