AbPlus™ Anti-HCN1 Magnetic Beads (VS-0724-YC444) (CAT#: VS-0724-YC444)
The AbPlus Anti-HCN1 Magnetic Beads (VS-0724-YC444) is an innovative affinity resin which is bound with anti-HCN1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of HCN1 protein under native and denaturing conditions.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 High expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_B_8_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_B_8_5_val_selected.jpg

Figure 2 Low expression in cervix
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_B_8_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_B_8_3_val_selected.jpg

Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_B_8_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_B_8_5.jpg

Figure 4 Testis
(Elongated or late spermatids Staining: Low Intensity: Weak Quantity: 75%-25% Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_A_6_6.jpg
(Elongated or late spermatids Staining: Low Intensity: Weak Quantity: 75%-25% Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Spermatogonia cells Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19195/169549_A_6_6.jpg

Figure 5 RNA cell line category: Cell line enhanced (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164588-HCN1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164588-HCN1
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-HCN1 specific antibody
- Target
- HCN1
- Immunogen
- Recombinant human HCN1 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The membrane protein encoded by this gene is a hyperpolarization-activated cation channel that contributes to the native pacemaker currents in heart and neurons. The encoded protein can homodimerize or heterodimerize with other pore-forming subunits to form a potassium channel. This channel may act as a receptor for sour tastes. [provided by RefSeq, Oct 2011]
- Alternative Names
- Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 1; Brain Cyclic Nucleotide-Gated Channel 1; BCNG-1; BCNG1; Potassium/Sodium Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 1; Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1; EIEE24; HAC-2;
- Gene ID
- 348980
- UniProt ID
- O60741
Downloads
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IgG Antibodies
IHC Kits & Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2473CT | Recombinant Mouse anti-Human HCN1 Monoclonal antibody (9I9) | WB | |
VS-0422-LC113 | Mouse Anti-HCN1 Recombinant Antibody (clone mN70/28) | ICC, WB, IF, IHC | Mouse IgG2a |
VS-0422-LC114 | Rat Anti-HCN1 Recombinant Antibody (clone rtN70/28) | ICC, WB, IF, IHC | Rat IgG2b |
VS-0422-LC115 | Human Anti-HCN1 Recombinant Antibody (clone hN70/28) | ICC, WB, IF, IHC | Human IgG1 |
VS-0422-LC116 | Rabbit Anti-HCN1 Recombinant Antibody (clone rN70/28) | ICC, WB, IF, IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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