Recombinant Mouse Anti-HCV E2 AS412 peptide Antibody (19B3) (CAT#: PABC-417)
This product is a recombinant Mouse antibody that can recognize HCV E2 AS412 peptide. 19B3 showed a lower Kd for all isolates. 19B3 has the highest neutralizing activity against the HCV isolates tested.
Specific Inquiry
Neut
Figure 1 Cross-genotype neutralization.
Neutralization breadth of antibodies against a panel of HCVpps. Data shown are means (μg/mL) of at least three neutralization experiments with SE (SEM).
Aleman, F., Tzarum, N., Kong, L., Nagy, K., Zhu, J., Wilson, I. A., & Law, M. (2018). Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proceedings of the National Academy of Sciences, 115(29), 7569-7574.
FuncS
Figure 2 Contribution of HC and LC for antibody function.
E1E2 binding experiments using mature and precursor variable domains of 19B3.
Aleman, F., Tzarum, N., Kong, L., Nagy, K., Zhu, J., Wilson, I. A., & Law, M. (2018). Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proceedings of the National Academy of Sciences, 115(29), 7569-7574.
Specifications
- Immunogen
- The hepatitis C virus (HCV) envelope glycoproteins E1E2
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- HCV E2 AS412 peptide
- Species Reactivity
- HCV genotypes 1a to 6a
- Clone
- 19B3
- Applications
- Neut, FuncS
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Neutralization and Function Assay.
Target
- Alternative Names
- HCV E2; Hepatitis C virus E2 protein; HCV E2 AS412 peptide
- UniProt ID
- P27958
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-416 | Recombinant Mouse Anti-HCV E2 AS412 peptide Antibody (22D11) | Neut, FuncS | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-416 | Recombinant Mouse Anti-HCV E2 AS412 peptide Antibody Fab Fragment (22D11) | ELISA, Neut | Mouse Fab |
| PFBC-417 | Recombinant Mouse Anti-HCV E2 AS412 peptide Antibody Fab Fragment (19B3) | ELISA, Neut | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-416 | Recombinant Mouse Anti-HCV E2 AS412 peptide Antibody scFv Fragment (22D11) | ELISA, Neut | Mouse scFv |
| PSBC-417 | Recombinant Mouse Anti-HCV E2 AS412 peptide Antibody scFv Fragment (19B3) | ELISA, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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