AbPlus™ Anti-HERC4 Magnetic Beads (VS-0724-YC157) (CAT#: VS-0724-YC157)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-HERC4 specific antibody

• Target
• HERC4

• Immunogen
• Recombinant human HERC4 fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]

• Alternative Names
• HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 4; HECT Domain And RCC1-Like Domain-Containing Protein 4; HECT-Type E3 Ubiquitin Transferase HERC4; Hect Domain And RLD 4; EC 2.3.2.26; KIAA1593; EC 6.3.2;

• Gene ID
• 26091

• UniProt ID
• Q5GLZ8

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