Recombinant Mouse Anti-HERV-K Antibody (HA-137) (CAT#: HPAB-0643-WJ)
This product is a mouse antibody targeting human HERV-K. This antibody can be used in various therapeutic and diagnostic applications.
Specific Inquiry
IF
Figure 1. Identification of linear Ab epitopes in HERV-K (HML-2) TM expressed by infected cells by Immunofluorescence.
Representative images of HERV-K TM surface expression on infected TZMbl cells. Original magnification 340. The detection of TM protein surface expression was performed by immunofluorescence on in vitro HIV-1LAI–infected TZMbl cells 2 d postinfection.
Michaud, H. A., SenGupta, D., De Mulder, M., Deeks, S. G., Martin, J. N., Kobie, J. J., ... & Nixon, D. F. (2014). Cutting Edge: An Antibody Recognizing Ancestral Endogenous Virus Glycoproteins Mediates Antibody-Dependent Cellular Cytotoxicity on HIV-1–Infected Cells. The Journal of Immunology, 193(4), 1544-1548.
FC
Figure 2. Representative flow cytometry plots depicting HA-137 extracellular binding on infected PBMCs.
HA-137 recognition was assessed by measuring the frequency of HA-137Alexa Fluor 488+ cells gated on live HIVGag+ or HIVGag2 cells from infected PBMCs.
Michaud, H. A., SenGupta, D., De Mulder, M., Deeks, S. G., Martin, J. N., Kobie, J. J., ... & Nixon, D. F. (2014). Cutting Edge: An Antibody Recognizing Ancestral Endogenous Virus Glycoproteins Mediates Antibody-Dependent Cellular Cytotoxicity on HIV-1–Infected Cells. The Journal of Immunology, 193(4), 1544-1548.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- HERV-K
- Species Reactivity
- HERV
- Clone
- HA-137
- Applications
- IF, FC
Applications
- Application Notes
- The HA-137 antibody has been reported in applications of IF, FC.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- ERVK-6; HERV-K; Endogenous Retrovirus Group K Member 6, Envelope
- Gene ID
- 64006
- UniProt ID
- Q9Y6I0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0133-YC | Human Anti-HERV-K Recombinant Antibody (HPAB-N0133-YC) | FC | Human IgG |
| HPAB-N0134-YC | Human Anti-HERV-K Recombinant Antibody (HPAB-N0134-YC) | FC | Human IgG |
| HPAB-0971WJ | Mouse Anti-HERV-K Recombinant Antibody (HPAB-0971WJ) | IF, FC, IHC | Mouse IgG |
| HPAB-0972WJ | Mouse Anti-HERV-K Recombinant Antibody (HPAB-0972WJ) | IHC, WB, FC | Mouse IgG |
| HPAB-0973WJ | Mouse Anti-HERV-K Recombinant Antibody (HPAB-0973WJ) | IHC, WB, FC | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0133-YC-S(P) | Human Anti-HERV-K Recombinant Antibody; scFv Fragment (HPAB-N0133-YC-S(P)) | FC | Human scFv |
| HPAB-N0134-YC-S(P) | Human Anti-HERV-K Recombinant Antibody; scFv Fragment (HPAB-N0134-YC-S(P)) | FC | Human scFv |
| HPAB-0643-WJ-S(P) | Recombinant Mouse Anti-HERV-K Antibody scFv Fragment (HA-137) | ELISA, WB | Mouse scFv |
| HPAB-0971WJ-S(P) | Mouse Anti-HERV-K Recombinant Antibody; scFv Fragment (HPAB-0971WJ-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0972WJ-S(P) | Mouse Anti-HERV-K Recombinant Antibody; scFv Fragment (HPAB-0972WJ-S(P)) | ELISA, WB | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0133-YC-F(E) | Human Anti-HERV-K Recombinant Antibody; Fab Fragment (HPAB-N0133-YC-F(E)) | FC | Human Fab |
| HPAB-N0134-YC-F(E) | Human Anti-HERV-K Recombinant Antibody; Fab Fragment (HPAB-N0134-YC-F(E)) | FC | Human Fab |
| HPAB-0643-WJ-F(E) | Recombinant Mouse Anti-HERV-K Antibody Fab Fragment (HA-137) | ELISA, WB | Mouse Fab |
| HPAB-0971WJ-F(E) | Mouse Anti-HERV-K Recombinant Antibody; Fab Fragment (HPAB-0971WJ-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0972WJ-F(E) | Mouse Anti-HERV-K Recombinant Antibody; Fab Fragment (HPAB-0972WJ-F(E)) | ELISA, WB | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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