Mouse Anti-HIV-1 Gag Recombinant Antibody (clone 3-H-7 (3H7)) (CAT#: MRO-2840CQ)

Recombinant mouse antibody to Gag(113-122). 3H7 can inhibit HIV-1 infection when expressed in the cytoplasm of dividing CD4+ T cells and HXBIIIB and SI primary isolate virions from 3H7 expressing cells were far less infectious.

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IP

Figure 1 Analysis of PIC activity and integrase and BAF proteins following immunoprecipitation with MAb 3H7.

Figure 1 Analysis of PIC activity and integrase and BAF proteins following immunoprecipitation with MAb 3H7.

Levels of HIV-1 cDNA synthesis in fraction I (lane 1) and integration activity of various fractions analyzed by Southern blotting. Target DNA was added to the in vitro integration assays shown in lanes 2 and 4 to 7 as indicated.

The Barrier-to-Autointegration Factor Is a Component of Functional Human Immunodeficiency Virus Type 1 Preintegration Complexes

IP

Figure 2 Coimmunoprecipitation of integration activity and integrase and BAF proteins by using anti-Ku and anti-Vpr antibodies.

Figure 2 Coimmunoprecipitation of integration activity and integrase and BAF proteins by using anti-Ku and anti-Vpr antibodies.

Southern blot analysis of HIV-1 cDNA synthesis (lane 1) and PIC activity. Target DNA was included in the in vitro integration reactions shown in lanes 2, 4, and 7 to 12.

The Barrier-to-Autointegration Factor Is a Component of Functional Human Immunodeficiency Virus Type 1 Preintegration Complexes


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Recognizes HIV-1 Gag(113-122)
  • Species Reactivity
  • HIV-1
  • Clone
  • 3-H-7 (3H7)
  • Applications
  • Neut, IP

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 Gag antibody has been reported in applications of Neutralization, Immunoprecipitation.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Gag

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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