Human Anti-HIV-1 gp120 Recombinant Antibody (clone F39F) (CAT#: MRO-3390CQ)
This product is a recombinant human anti-HIV-1 monoclonal antibody. F39F specifically binds to gp120.
Specific Inquiry
Block
Figure 1 The majority of HIV-1 Env antibodies do not block Galcer binding of a T/F virus Env, but a few RV135/144 vaccinee-derived antibodies do partially block Galcer binding.
Comparison of the percent blocking of Galcer liposome binding of 1086.C gp140 by sCD4, gp120 CD4 binding site-specific MAbs VRC01and b12, CD4i epitope binding MAb 17B with and without sCD4, gp120 V3 loop-specific MAbs 19B and F39F, glycan-specific gp120 MAb 2G12, glycan-dependent gp120 V1V2 MAbs PG9 and CH01, gp120 C1 region-specific MAb A32, gp41 immunodominant loop-specific MAb 7B2 and gp41, and membrane-proximal external region-specific MAbs 2F5, 4E10, and 13H11.
Dennison, S. M., Anasti, K. M., Jaeger, F. H., Stewart, S. M., Pollara, J., Liu, P., ... & Ferrari, G. (2014). Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide. Journal of virology, 88(16), 9406-9417.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Recognizes HIV-1 gp120
- Species Reactivity
- HIV-1
- Clone
- F39F
- Applications
- ELISA, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Blocking Assay.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone F39F"
See other products for "HIV-1 gp120"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-082 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-028LC-VHH) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-029LC-VHH) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-030LC-VHH) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-031LC-VHH) | ELISA | Single domain antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06) | FC, Neut, FuncS | Human IgG |
| PABZ-164 | Human Anti-HIV-1 gp120 Recombinant Antibody (PABZ-164) | ELISA, Neut | Human IgG |
| PABZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01) | Neut | Human IgG |
| PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
| PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-46M2) | ELISA, Neut | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-041LC | Anti-HIV-1 gp120 Recombinant Antibody (D59/A2) | ELISA | Mouse antibody |
| MRO-042LC | Anti-HIV-1 gp120 Recombinant Antibody (F58/H3) | WB, ELISA | Mouse antibody |
| MRO-043LC | Anti-HIV-1 gp120 Recombinant Antibody (P1/D12) | ELISA | Mouse antibody |
| MRO-044LC | Anti-HIV-1 gp120 Recombinant Antibody (P4/D10) | ELISA | Mouse antibody |
| MRO-045LC | Anti-HIV-1 gp120 Recombinant Antibody (A47/B1) | ELISA | Mouse antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
| MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
| MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
| MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
| MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-3321CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H5dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3322CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H6dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3323CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H7dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3324CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H8dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3325CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone gVRC-H9dC38/VRC01L); Fab Fragment | ELISA, Neut | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0048-YC-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 3019); scFv Fragment | ELISA | Human scFv |
| FAMAB-0056WJ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone L17); scFv Fragment | ELISA, Neut | Human scFv |
| FAMAB-0058WJ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone P20); scFv Fragment | ELISA, Neut | Human scFv |
| PSBS-0130 | Human Anti-HIV-1 gp120 Recombinant Antibody (Clone VRC01cHuGL2); scFv Fragment | ELISA, FuncS | Human scFv |
| PABJ-0086-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone DH677.3); scFv Fragment | ELISA, ADCC | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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