Human Anti-HIV-1 gp120 Recombinant Antibody (clone 43D7) (CAT#: MRO-3467CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. 43D7 specifically binds to gp120.


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ELISA

Figure 1 Effect of sCD4 over binding of MAbs isolated from patient KTS376 to monomeric SF2gp120.

Figure 1 Effect of sCD4 over binding of MAbs isolated from patient KTS376 to monomeric SF2gp120.

Reactivity to gp120 was examined for 43D7 mAb alone (gray diamond) or in the presence of sCD4 (black square) by capture ELISA assay.

Valdez, K. P., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., & Matsushita, S. (2015). Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains.. Virology,, 187-203.

FC

Figure 2 Binding of MAbs from patient KTS376 to Env expressed on the surface of cells.

Figure 2 Binding of MAbs from patient KTS376 to Env expressed on the surface of cells.

Mean fluorescence intensity is shown for 43D7 mAb in the presence (gray) or absence (black) of sCD4.

Valdez, K. P., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., & Matsushita, S. (2015). Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains.. Virology,, 187-203.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG2, κ
  • Specificity
  • Recognizes HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • 43D7
  • Applications
  • ELISA, FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Flow Cytometry and Enzyme-Linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 43D7"

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Single-domain Antibody

Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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