Human Anti-HIV-1 gp120 Recombinant Antibody (clone 2-1092) (CAT#: MRO-3274CQ)
Recombinant human antibody to gp120. This Ab can bind to gp160 trimer lacking the cytoplasmic domain and to gp140 with high affinity and retained its high affinity binding to gp160 or gp140 with three mutations (D747A, M475A and R476A).
Specific Inquiry
ELISA
Figure 1 Binding to soluble and cell surface trimeric gp160△c.
Graphs show optical density at 405 nm (OD405nm) for the selected IgG antibodies as measured by capture ELISA with purified BaL gp140 WT and BaL gp140. Error bars represent the SD from at least two independent experiments.
Pietzsch, J., Scheid, J. F., Mouquet, H., Klein, F., Seaman, M. S., Jankovic, M., ... & Nussenzweig, M. C. (2010). Human anti–HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness. Journal of Experimental Medicine, 207(9), 1995-2002.
FC
Figure 2 Binding to soluble and cell surface trimeric gp160△c.
The number of binding events as percentage of the maximum was plotted against APC fluorescence intensity.
Pietzsch, J., Scheid, J. F., Mouquet, H., Klein, F., Seaman, M. S., Jankovic, M., ... & Nussenzweig, M. C. (2010). Human anti–HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness. Journal of Experimental Medicine, 207(9), 1995-2002.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Recognizes HIV-1 gp120
- Species Reactivity
- HIV-1
- Clone
- 2-1092
- Applications
- ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay and Flow Cytometry.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 2-1092"
See other products for "HIV-1 gp120"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06); scFv Fragment | Neut, FuncS | Human scFv |
| PFBZ-164 | Human Anti-HIV-1 gp120 Recombinant Antibody; Fab Fragment (PFBZ-164) | Neut | Human Fab |
| PFBZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01); Fab Fragment | Neut | Human Fab |
| MRO-3505CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone Q10); scFv Fragment | ELISA, FC | Human scFv |
| MRO-3638CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 9305); scFv Fragment | Neut | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-164 | Human Anti-HIV-1 gp120 Recombinant Antibody; scFv Fragment (PSBZ-164) | Neut | Human scFv |
| PSBZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01); scFv Fragment | Neut | Human scFv |
| PSBW-160 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone F105); scFv Fragment | FC, Neut | Human scFv |
| PSBW-178 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone b12); scFv Fragment | Neut, ELISA | Human scFv |
| MRO-3076CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone BF520.4); Fab Fragment | Neut | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-028LC-VHH) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-029LC-VHH) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-030LC-VHH) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-031LC-VHH) | ELISA | Single domain antibody |
| MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (MRO-032LC-VHH) | ELISA | Single domain antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-041LC | Anti-HIV-1 gp120 Recombinant Antibody (D59/A2) | ELISA | Mouse antibody |
| MRO-042LC | Anti-HIV-1 gp120 Recombinant Antibody (F58/H3) | WB, ELISA | Mouse antibody |
| MRO-043LC | Anti-HIV-1 gp120 Recombinant Antibody (P1/D12) | ELISA | Mouse antibody |
| MRO-044LC | Anti-HIV-1 gp120 Recombinant Antibody (P4/D10) | ELISA | Mouse antibody |
| MRO-045LC | Anti-HIV-1 gp120 Recombinant Antibody (A47/B1) | ELISA | Mouse antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
| MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
| MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
| MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
| MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2972CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1-479) | Neut | Human IgG |
| MRO-2973CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1-577) | Neut | Human IgG |
| MRO-2974CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1595) | ELISA | Human IgG1, κ |
| MRO-2975CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1599) | ELISA | Human IgG1, λ |
| MRO-2976CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1-621) | Neut | Human IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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