Monkey Anti-HIV-1 gp120 Recombinant Antibody (GE443) (CAT#: HPAB-0714-YJ)
This product is a recombinant Monkey antibody that recognizes HIV-1 gp120.
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Custom Production
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ELISA
Figure 1 Isolation of HIV-1 gp120 CD4bs-specific vaccine-induced NHP memory B cells, NHP MAbs and their binding specificities.
Four VH1.23-using MAbs (GE331, GE356, GE443 and GE453) were characterized for their capacity to bind trimeric gp140-F+/−D368R and TriMut+/−368/370 by ELISA. Titration curves are shown as Log₁₀ dilutions (µg/ml). All antibodies were isolated from the post 2 immunization time point.
Navis, M., Tran, K., Bale, S., Phad, G. E., Guenaga, J., Wilson, R., ... & Li, Y. (2014). HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization. PLoS pathogens, 10(8), e1004337.
Specifications
- Immunogen
- The soluble gp140-F trimers.
- Host Species
- Monkey
- Type
- Monkey IgG, κ
- Specificity
- HIV-1
- Species Reactivity
- HIV-1
- Clone
- GE443
- Applications
- ELISA
- Related Disease
- AIDS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- HIV-1 envelope glycoprotein gp120; gp120; HIV-1 gp120; HIV-1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06) | FC, Neut, FuncS | Human IgG |
| PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
| PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (PABL-521) | ELISA, Neut | Human IgG |
| PABL-522 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-VRC01.H5.F-185917) | WB, FuncS | Human IgG |
| PABL-523 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 8ANC131) | WB, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
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