Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone D61) (CAT#: MRO-3990CQ)
This product is a recombinant mouse anti-HIV-1 monoclonal antibody. D61 specifically binds to gp160(592-608).
Specific Inquiry
WB
Figure 1 Analysis of wild-type and LQA/CCG envelope glycoproteins.
Upon boiling the mutant protein in higher concentrations of b-mercaptoethanol.
Farzan, M., Choe, H., Desjardins, E., Sun, Y., Kuhn, J., Cao, J., ... & Sodroski, J. (1998). Stabilization of human immunodeficiency virus type 1 envelope glycoprotein trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain. Journal of virology, 72(9), 7620-7625.
IF
Figure 2 Specific infection of CD41 cells after neutralization of VSV-G.
Cells were fixed after 8 h and stained by immunofluorescence with a mixture of anti-VSV G MAbs and rhodamine-conjugated donkey anti-mouse antibodies.
Johnson, J. E., Schnell, M. J., Buonocore, L. I. N. D. A., & Rose, J. K. (1997). Specific targeting to CD4+ cells of recombinant vesicular stomatitis viruses encoding human immunodeficiency virus envelope proteins. Journal of virology, 71(7), 5060-5068.
Block
Figure 3 Mapping of conformation-dependent MAbs by blocking.
The anti-gp41 linear MAbs were used as landmarks to map the regions of gp41 necessary for binding by conformation-dependent MAbs.
Earl, P. L., Broder, C. C., Doms, R. W., & Moss, B. (1997). Epitope map of human immunodeficiency virus type 1 gp41 derived from 47 monoclonal antibodies produced by immunization with oligomeric envelope protein. Journal of Virology, 71(4), 2674-2684.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Recognizes HIV-1 gp160(592-608)
- Species Reactivity
- HIV-1
- Clone
- D61
- Applications
- WB, IF, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Western Blot, Immunofluorescence, Blocking. WB: Lysates
were immunoprecipitated with the anti-gp41 antibody D61 and boiled in either
2 or 5% b-mercaptoethanol (bME) for 3 or 10 min, as indicated, before being
analyzed on an SDS–8% polyacrylamide gel.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody (PABL-177) | WB, ELISA, Neut, FuncS | Human IgG |
| PABL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L) | WB, ELISA, FuncS | Human IgG |
| PABL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128) | WB, ELISA, FuncS | Human IgG |
| PABL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C) | WB, ELISA, Neut, FuncS | Human IgG, κ |
| PABL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01) | FC, Neut, FuncS | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; scFv Fragment (PSBL-177) | WB, ELISA, Neut, FuncS | Human scFv |
| PSBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); scFv Fragment | WB, ELISA, Neut, FuncS | Human scFv |
| PSBL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08); scFv Fragment | Neut, FuncS | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; Fab Fragment (PFBL-177) | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01); Fab Fragment | FC, Neut, FuncS | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-075LC | Anti-HIV-1 gp160 Recombinant Antibody (24G3) | WB, ELISA | Human antibody |
| MRO-080LC | Anti-HIV-1 gp160 Recombinant Antibody (81C7) | ELISA | Human antibody |
| MRO-091LC | Anti-HIV-1 gp160 Recombinant Antibody (MAb CL1) | ELISA | Human antibody |
| MRO-100LC | Anti-HIV-1 gp160 Recombinant Antibody (N7019b) | ELISA | Human antibody |
| MRO-075LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (24G3) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-086LC | Anti-HIV-1 gp160 Recombinant Antibody (1C1) | ELISA | Mouse antibody |
| MRO-087LC | Anti-HIV-1 gp160 Recombinant Antibody (1H9) | ELISA | Mouse antibody |
| MRO-089LC | Anti-HIV-1 gp160 Recombinant Antibody (2H8) | ELISA | Mouse antibody |
| MRO-086LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1C1) | ELISA | Mouse antibody |
| MRO-087LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1H9) | ELISA | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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