Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 133/192) (CAT#: MRO-3917CQ)
Recombinant mouse antibody to gp160(91-100). The relative affinity for denatured/native gp120 is 1.8. Epitope seems complex, binds multiple peptides and weak neutralization of lab strain.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
IF
Figure 1 HIV-1 strain HTLV-IIIB was cultured in H9 cells after incubation with MAb 133/192 and anti-mouse IgG-ferritin.
Bar marker represents 100 nm.
Niedrig, M., Harthus, H. P., Hinkula, J., Bröker, M., Bickhard, H., Pauli, G., ... & Wahren, B. (1992). Inhibition of viral replication by monoclonal antibodies directed against human immunodeficiency virus gp120. Journal of general virology, 73(9), 2451-2455.
ELISA
Figure 2 Effect of repeated treatment of fresh HIV-1-infected cells with purified MAbs.
The arrows indicate the different antibodies was added at the time points.
Niedrig, M., Harthus, H. P., Hinkula, J., Bröker, M., Bickhard, H., Pauli, G., ... & Wahren, B. (1992). Inhibition of viral replication by monoclonal antibodies directed against human immunodeficiency virus gp120. Journal of general virology, 73(9), 2451-2455.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Recognizes HIV-1 gp160(91-100)
- Species Reactivity
- HIV-1
- Clone
- 133/192
- Applications
- ELISA, IF
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunofluorescence. ELISA: The cultures were supplemented with 63 ug/ml of the antibodies:
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; Fab Fragment (PFBL-177) | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (PFBL-178) | WB, ELISA, FuncS | Human Fab |
| PFBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01); Fab Fragment | FC, Neut, FuncS | Human Fab |
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