Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone 5A9) (CAT#: MRO-3961CQ)
Recombinant mouse antibody to gp160. This is a novel murine MAb that partially blocked 2F5 MAb binding to ENV but did not neutralize primary isolates or bind host lipids.
Specific Inquiry
IF
Figure 1 Reactivity of HIV-1.Env gp41 cluster II MAbs with the surface of HIV-1-infected T cells.
Shown are histograms of viable H9 HIV-1-infected T cells reacted with the indicated MAbs in indirect immunofluorescence assays.
Alam, S. M., Scearce, R. M., Parks, R. J., Plonk, K., Plonk, S. G., Sutherland, L. L., ... & Xia, S. M. (2008). Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection. Journal of virology, 82(1), 115-125.
Block
Figure 2 Cross-blocking of 13H11 MAb (5A9) binding to HR-2 peptide.
Biotin–HR-2 (about 200 RU) peptide was anchored on a streptavidin chip (Biacore SA chip) and either blocking antibody 13H11.
Alam, S. M., Scearce, R. M., Parks, R. J., Plonk, K., Plonk, S. G., Sutherland, L. L., ... & Xia, S. M. (2008). Human immunodeficiency virus type 1 gp41 antibodies that mask membrane proximal region epitopes: antibody binding kinetics, induction, and potential for regulation in acute infection. Journal of virology, 82(1), 115-125.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Recognizes HIV-1 gp160
- Species Reactivity
- HIV-1
- Clone
- 5A9
- Applications
- IF, Block
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Immunofluorescence, Blocking.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone 5A9"
See other products for "HIV-1 gp160"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; scFv Fragment (PSBL-177) | WB, ELISA, Neut, FuncS | Human scFv |
| PSBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); scFv Fragment | WB, ELISA, Neut, FuncS | Human scFv |
| PSBC-305 | Human Anti-HIV-1 gp160 Recombinant Antibody; scFv Fragment (PSBC-305) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; Fab Fragment (PFBL-177) | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 3H+109L); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01); Fab Fragment | FC, Neut, FuncS | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-075LC | Anti-HIV-1 gp160 Recombinant Antibody (24G3) | WB, ELISA | Human antibody |
| MRO-080LC | Anti-HIV-1 gp160 Recombinant Antibody (81C7) | ELISA | Human antibody |
| MRO-091LC | Anti-HIV-1 gp160 Recombinant Antibody (MAb CL1) | ELISA | Human antibody |
| MRO-100LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (N7019b) | ELISA | Human antibody |
| MRO-101LC-S(P) | Anti-HIV-1 gp160 Recombinant Antibody scFv Fragment (K24-3b) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-086LC | Anti-HIV-1 gp160 Recombinant Antibody (1C1) | ELISA | Mouse antibody |
| MRO-087LC | Anti-HIV-1 gp160 Recombinant Antibody (1H9) | ELISA | Mouse antibody |
| MRO-089LC | Anti-HIV-1 gp160 Recombinant Antibody (2H8) | ELISA | Mouse antibody |
| MRO-086LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1C1) | ELISA | Mouse antibody |
| MRO-087LC-F(E) | Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (1H9) | ELISA | Mouse antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-3673CQ | Chimpanzee Anti-HIV-1 gp160 Recombinant Antibody (clone C311E) | FC, FuncS | Chimpanzee IgG1 |
| MRO-3674CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone HGN35) | ELISA | Human IgG |
| MRO-3675CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-188) | Neut, WB, ELISA | Human IgG |
| MRO-3676CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10-380) | Neut | Human IgG |
| MRO-3677CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 10J4) | Neut | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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