Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone B9) (CAT#: MRO-3978CQ)

This product is a recombinant mouse anti-HIV-1 monoclonal antibody. B9 specifically binds to gp160(93-96).

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ELISA

Figure 4 B21 binding to HIV ENV.

Figure 4 B21 binding to HIV ENV.

YU2 WT and D368R gp120 mutant gp120, was assessed by ELISA.

McCoy, L. E., Rutten, L., Frampton, D., Anderson, I., Granger, L., Bashford-Rogers, R., ... & Grippo, V. (2014). Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1. PLoS Pathog, 10(12), e1004552.

Neut

Figure 5 VHH mutation alters affinity, potency and breadth of neutralization.

Figure 5 VHH mutation alters affinity, potency and breadth of neutralization.

VHH binding to clade B gp120 Bal.26 in ELISA detected by their C-terminal Myc tag.

McCoy, L. E., Rutten, L., Frampton, D., Anderson, I., Granger, L., Bashford-Rogers, R., ... & Grippo, V. (2014). Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1. PLoS Pathog, 10(12), e1004552.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • Recognizes HIV-1 gp160(93-96)
  • Species Reactivity
  • HIV-1
  • Clone
  • B9
  • Applications
  • IF, WB, FC, ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp160 antibody has been reported in applications of Immunofluorescence, Western Blot, Flow Cytometry, Enzyme-linked Immunosorbent Assay, Neutralization.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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