Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone SAR1) (CAT#: MRO-3960CQ)
Recombinant mouse antibody to gp160(738-744). This ERDRD-specific MAb recognizes an externalized loop of the gp41 C-terminal domain, and can reduce the yield of infectious progeny and inhibit fusion post-attachment, but not neutralize free virus.
Specific Inquiry
FC
Figure 2 FACS analysis of intact Env-expressing cells demonstrates extracellular exposure of the KE sequence.
Intact cells expressing Env were stained for surface exposure of the KE using a native KE antibody, SAR1.
Steckbeck, J. D., Sun, C., Sturgeon, T. J., & Montelaro, R. C. (2010). Topology of the C-terminal tail of HIV-1 gp41: differential exposure of the Kennedy epitope on cell and viral membranes. PloS one, 5(12).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Recognizes HIV-1 gp160(738-744)
- Species Reactivity
- HIV-1
- Clone
- SAR1
- Applications
- FC, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Flow Cytometry, Neutralization.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Fab Antibody Products
Human Antibody Products
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ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-177 | Human Anti-HIV-1 gp160 Recombinant Antibody; Fab Fragment (PFBL-177) | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-178 | Human Anti-HIV-1 gp160 Recombinant Antibody Fab Fragment (PFBL-178) | WB, ELISA, FuncS | Human Fab |
| PFBL-179 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128); Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-180 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08C); Fab Fragment | WB, ELISA, Neut, FuncS | Human Fab |
| PFBL-181 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC13.01); Fab Fragment | FC, Neut, FuncS | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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