Mouse Anti-HIV-1 gp160 Recombinant Antibody (clone SAR1) (CAT#: MRO-3960CQ)
Recombinant mouse antibody to gp160(738-744). This ERDRD-specific MAb recognizes an externalized loop of the gp41 C-terminal domain, and can reduce the yield of infectious progeny and inhibit fusion post-attachment, but not neutralize free virus.
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FC
Figure 2 FACS analysis of intact Env-expressing cells demonstrates extracellular exposure of the KE sequence.
Intact cells expressing Env were stained for surface exposure of the KE using a native KE antibody, SAR1.
Steckbeck, J. D., Sun, C., Sturgeon, T. J., & Montelaro, R. C. (2010). Topology of the C-terminal tail of HIV-1 gp41: differential exposure of the Kennedy epitope on cell and viral membranes. PloS one, 5(12).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Recognizes HIV-1 gp160(738-744)
- Species Reactivity
- HIV-1
- Clone
- SAR1
- Applications
- FC, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 gp160 antibody has been reported in applications of Flow Cytometry, Neutralization.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP160; gp160; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
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Human Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-382 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone VRC08) | Neut, FuncS | Human IgG, κ |
| PABW-163 | Human Anti-HIV-1 gp160 Recombinant Antibody (clone 268-D) | ELISA, Neut | Human IgG1,λ |
| MRO-3710CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone CH423) | ELISA | Human IgG1 |
| MRO-3712CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone DZ) | ELISA, WB, Neut, FC | Human IgG1, λ |
| MRO-3713CQ | Human Anti-HIV-1 gp160 Recombinant Antibody (clone F172-D8 (F172-D8, D8)) | ELISA, WB, IF | Human IgG |
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