Recombinant Llama Anti-HIV-1 p24 Single Domain Antibody (PABC-580) (CAT#: PABC-580)
This product is a recombinant Llama antibody that can recognize HIV-1 p24.
Specific Inquiry
ELISA
Figure 1 A sandwich ELISA was performed to assess detection of 50 viral strains from the EQAPOL viral subtype diversity panel.
The ELISA was in a sandwich format with a mAb capture antibody (CP-HIV-1/2) and 59H10 detection sdAb. Error bars show standard deviation of the mean from at least 6 wells across 2 or 3 independent experiments.
Gray, E. R., Brookes, J. C., Caillat, C., Turbé, V., Webb, B. L., Granger, L. A., ... & Weiss, R. A. (2017). Unravelling the molecular basis of high affinity sdAbs against HIV p24: in vitro functional, structural, and in silico insights. ACS infectious diseases, 3(7), 479-491.
Specifications
- Host Species
- Llama
- Type
- Llama VHH
- Specificity
- HIV-1 p24
- Species Reactivity
- HIV-1 group M subtype B
- Clone
- PABC-580
- Applications
- ELISA
- Related Disease
- HIV infection
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Capsid protein p24; p24
- UniProt ID
- P12493
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-187 | Human Anti-HIV-1 p24 Recombinant Antibody (clone 5) | ELISA, WB, IF | Chimeric IgG1 |
| MRO-958CQ | Mouse Anti-HIV-1 P24 Recombinant Antibody (clone 8G9) | ELISA, WB | Mouse IgG |
| MRO-959CQ | Mouse Anti-HIV-1 p24 Recombinant Antibody (MRO-959CQ) | ELISA | Mouse IgG1 |
| MRO-960CQ | Mouse Anti-HIV-1 p24 Recombinant Antibody (MRO-960CQ) | ELISA, RIA | Mouse IgG1 |
| MRO-961CQ | Mouse Anti-HIV-1 p24 Recombinant Antibody (clone AG3.0) | ELISA | Mouse IgG1 |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABC-580, RRID: AB_3111602)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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