Mouse Anti-HIV-1 pol Recombinant Antibody (clone 17 (mAb17)) (CAT#: MRO-4264CQ)
Recombinant mouse antibody to Pol(740-750). Epitope of the antibody mapped to helix-turn-helix motif in the N-term domain of Integrase, positions 25-35 - Zn binding stabilizes the Integrase. mAb17 inhibit Integrase activity.
Specific Inquiry
ELISA
Figure 1 Structural and functional domains of HIV-1 IN and its interaction with mAb17.
The inhibitions of the processing activity of HIV-1 IN by mAb17 and Fab17 and control mAb (aMOPC12).
Yi, J., Arthur, J. W., Dunbrack, R. L., & Skalka, A. M. (2000). An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase. Journal of Biological Chemistry, 275(49), 38739-38748.
Specifications
- Immunogen
- Rec integrase
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Recognizes HIV-1 Pol(740-750)
- Species Reactivity
- HIV-1
- Clone
- 17 (mAb17)
- Applications
- ELISA, WB, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HIV-1 pol antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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