Recombinant Anti-ERBB2 Recombinant Triparatopic Antibody, Asymmetric CODV-Ig-Fab (CAT#: VS-0525-YC8)

The triparatopic antibody includes a dual-specificity crossover dual-variable Ig-like (CODVIg) arm paired with a Fab arm of a third, unique specificity. This triparatopic broadly neutralizing antibody (bnAb) is more effective at reducing viral load and preventing infection in a simian-human immunodeficiency virus (SHIV) challenge model in non-human primates.

Specific Inquiry
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • HIV Env
  • Species Reactivity
  • HIV
  • Type
  • Asymmetric CODV-Ig-Fab
  • Valency
  • 1 + 1 + 1
  • Epitope 1
  • The CD4 binding site
  • Epitope 2
  • The V1/V2 glycan and the membrane proximal external region
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, Neut
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • HIV1 envelope (Env) glycoprotein

Target

  • Introduction
  • Glycoprotein Gp160 is a viral surface protein encoded by the HIV1 env gene, which is cleaved into two envelope proteins, gp120 and gp41.
  • Alternative Names
  • ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain

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