Recombinant Anti-ERBB2 Recombinant Triparatopic Antibody, Asymmetric CODV-Ig-Fab
CAT#: VS-0525-YC8
The triparatopic antibody includes a dual-specificity crossover dual-variable Ig-like (CODVIg) arm paired with a Fab arm of a third, unique specificity. This triparatopic broadly neutralizing antibody (bnAb) is more effective at reducing viral load and preventing infection in a simian-human immunodeficiency virus (SHIV) challenge model in non-human primates.
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- HIV Env
- Species Reactivity
- HIV
- Type
- Asymmetric CODV-Ig-Fab
- Valency
- 1 + 1 + 1
- Epitope 1
- The CD4 binding site
- Epitope 2
- The V1/V2 glycan and the membrane proximal external region
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, Neut
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- HIV1 envelope (Env) glycoprotein
Target
- Introduction
- Glycoprotein Gp160 is a viral surface protein encoded by the HIV1 env gene, which is cleaved into two envelope proteins, gp120 and gp41.
- Alternative Names
- ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
- Gene ID
- 155971
- UniProt ID
- P04578
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-323 | Recombinant Anti-HIV Env Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-323 | Recombinant Human Anti-HIV Env Antibody | ELISA, WB, Dot, FuncS | IgG |
| PABL-508 | Human Anti-HIV Env Recombinant Antibody (clone 10-1074) | FC, FuncS | Human IgG |
| PABL-509 | Human Anti-HIV Env Recombinant Antibody (clone PGT121) | ELISA, Neut | Human IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-323-F(E) | Recombinant Anti-HIV Env Antibody Fab Fragment | IF, FC, FuncS | Fab |
| MHH-323-F(E) | Recombinant Human Anti-HIV Env Antibody Fab Fragment | IF, FuncS | Fab |
| PFBL-505 | Human Anti-HIV Env Recombinant Antibody (clone 10-1074); Fab Fragment | ELISA, Neut | Human Fab |
| PFBL-506 | Human Anti-HIV Env Recombinant Antibody (clone PGT121); Fab Fragment | ELISA, Neut | Human Fab |
| PABJ-0117-F(E) | Rabbit Anti-HIV Env Recombinant Antibody Fab Fragment (PABJ-0117-F(E)) | ELISA, Neut | Rabbit Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-323-S(P) | Recombinant Anti-HIV Env Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| PSBL-505 | Human Anti-HIV Env Recombinant Antibody (clone 10-1074); scFv Fragment | ELISA, Neut | Human scFv |
| PSBS-0064 | Human Anti-HIV ENV Recombinant Antibody (Clone GEP 1); scFv Fragment | ELISA, Neut, FuncS | Human scFv |
| PSBS-0113 | Human Anti-HIV ENV Recombinant Antibody (Clone PG9_N100FY); scFv Fragment | ELISA, Neut, FuncS | Human scFv |
| PABJ-0117-S(P) | Rabbit Anti-HIV Env Recombinant Antibody scFv Fragment (PABJ-0117-S(P)) | ELISA, Neut | Rabbit scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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