Recombinant Anti-ERBB2 Recombinant Triparatopic Antibody, Asymmetric CODV-Ig-Fab
CAT#: VS-0525-YC8
The triparatopic antibody includes a dual-specificity crossover dual-variable Ig-like (CODVIg) arm paired with a Fab arm of a third, unique specificity. This triparatopic broadly neutralizing antibody (bnAb) is more effective at reducing viral load and preventing infection in a simian-human immunodeficiency virus (SHIV) challenge model in non-human primates.
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- HIV Env
- Species Reactivity
- HIV
- Type
- Asymmetric CODV-Ig-Fab
- Valency
- 1 + 1 + 1
- Epitope 1
- The CD4 binding site
- Epitope 2
- The V1/V2 glycan and the membrane proximal external region
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, Neut
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- HIV1 envelope (Env) glycoprotein
Target
- Introduction
- Glycoprotein Gp160 is a viral surface protein encoded by the HIV1 env gene, which is cleaved into two envelope proteins, gp120 and gp41.
- Alternative Names
- ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
- Gene ID
- 155971
- UniProt ID
- P04578
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Datasheet
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COA
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| MOB-323-F(E) | Recombinant Anti-HIV Env Antibody Fab Fragment | IF, FC, FuncS | Fab |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| MHH-323-S(P) | Recombinant Human Anti-HIV Env Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| PFBL-505 | Human Anti-HIV Env Recombinant Antibody (clone 10-1074); Fab Fragment | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
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| PFBL-506 | Human Anti-HIV Env Recombinant Antibody (clone PGT121); Fab Fragment | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
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| PSBL-505 | Human Anti-HIV Env Recombinant Antibody (clone 10-1074); scFv Fragment | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
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| PSBL-506 | Human Anti-HIV Env Recombinant Antibody (clone PGT121); scFv Fragment | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| PFBS-0064 | Human Anti-HIV ENV Recombinant Antibody (Clone GEP 1); Fab Fragment | ELISA, Neut, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
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| PSBS-0064 | Human Anti-HIV ENV Recombinant Antibody (Clone GEP 1); scFv Fragment | ELISA, Neut, FuncS | Human scFv |
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