Human Anti-HLA-A2/gp100 Recombinant Antibody (VS-0524-YC5)
CAT#: VS-0524-YC5
The antibodies recognize the common HLA-A2-restricted epitopes IMDQVPFSV, YLEPGPVTV or KTWGQYWQV of the human melanoma differentiation antigen gp100. The antibodies recognizes HLA-A2 molecules only when displaying the specific peptide against which they were selected. They do not bind HLA-A2 molecules complexed with other gp100-derived epitopes or with other HLA-A2-restricted control peptides. They exhibit a TCR-like restriction. These antibodies have been used to directly visualize the specific HLA-A2/gp100 epitopes on antigen-presenting cells as well as on the surface of melanoma tumor cells by flow cytometry.
| Sub Cat | Clone | Epitope | Size | Conjugation | Endotoxin | Purity | Fc Engineering | |
| VS-0524-YC51 | 1A11 | HLA-A2/gp100 (IMDQVPFSV) complex | ||||||
| VS-0524-YC6 | 2B2 | HLA-A2/gp100 (YLEPGPVTV) complex | ||||||
| VS-0524-YC7 | G2D12 | HLA-A2/gp100 (KTWGQYWQV) complex |
More Infomation
Specifications
- Host Species
- Human
- Derivation
- Non-immune repertoire of phage antibody library
- Type
- Human IgG
- Specificity
- The gp100-derived peptide in complex with HLA-A2
- Species Reactivity
- Human
- Applications
- ELISA, FC
Product Property
- Purification
- Protein A purified
- Purity
- >95%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservative
- Storage
- Centrifuge briefly prior to opening vial. Store at 4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- HLA-A2; gp100; IMDQVPFSV; HLA-A2/gp100 (IMDQVPFSV) complex
- Long Name
- HLA-A2/melanocyte lineage-specific membrane glycoprotein gp100
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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