1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Mouse Anti-HMGB1 Recombinant Antibody (clone 3E8) (CAT#: HPAB-0215-FY)

    This product is a recombinant antibody that recognizes Human HMGB1. The monoclonal antibody 3E 8 reacts with the epitope of HMGB1.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line RH-30
    Figure 1 IF staining of human cell line RH-30
    (Immunofluorescent staining of human cell line RH-30 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73663/2043_F12_32_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/617_A1_1_selected.jpg
    Figure 3 IHC staining of human bone marrow
    Figure 3 IHC staining of human bone marrow
    (Immunohistochemical staining of human bone marrow shows strong nuclear positivity in hematopoietic cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_B_4_4_selected.jpg
    Figure 4 IHC staining of human esophagus
    Figure 4 IHC staining of human esophagus
    (Immunohistochemical staining of human esophagus shows strong nuclear positivity in squamous epithelial cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/ihc_selected.jpg
    Figure 5 IF staining of human cell line U-2 OS
    Figure 5 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/613_A1_1_red_green.jpg
    Figure 6 IF staining of human cell line U-251 MG
    Figure 6 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5873/610_A1_1_red_green.jpg
    Normal Tissue
    Figure 7 Cerebral cortex
    Figure 7 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Glial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_B_8_5.jpg
    Figure 8 Colon
    Figure 8 Colon
    (Endocrine cells
    Staining: High
    Intensity: Strong
    Endothelial cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Enterocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_9_3.jpg
    Figure 9 Liver
    Figure 9 Liver
    (Cholangiocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Hepatocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_8_4.jpg
    Figure 10 Kidney
    Figure 10 Kidney
    (Cells in glomeruli
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_7_5.jpg
    Figure 11 Lymph node
    Figure 11 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3506/10525_A_8_8.jpg
    RNA Expression
    Figure 12 RNA cell line category: Low cell line specificity
    Figure 12 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000189403-HMGB1
    Figure 12 RNA cell line category: Low cell line specificity
    Figure 12 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000189403-HMGB1

    Specifications

    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • Human HMGB1
    • Species Reactivity
    • Human
    • Clone
    • 3E8
    • Applications
    • Block, WB
    • Related Disease
    • Sepsis, systemic inflammatory response syndrome or acute lung injury, the autoimmune disease

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE and HPLC analysis
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • The HMGB1 antibody has been reported in applications of Western Blot, Blocking. WB: Raw264.7 cells were stimulated with 1 µg/ml HMGB1 for 8 hours, with or without 50 µg/ml of the antibodies indicated.

    Target

    • Alternative Names
    • High Mobility Group Box 1; High-Mobility Group (Nonhistone Chromosomal) Protein 1; Sulfoglucuronyl Carbohydrate Binding Protein; High Mobility Group Protein 1; Amphoterin; HMG-1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone 3E8"

    See other products for "HMGB1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Mouse Antibody Products Humanized Antibody Products Human Antibody Products Rabbit Monoclonal Antibody Products MHC Tetramer Products for Cancer ScFv Antibody Products Fab Antibody Products IgM Antibody Products Antibody Magnetic Beads IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    DrMAB-956 Human Anti-HMGB1 Recombinant Antibody (clone Giby-1-4) ELISA, WB Human IgG
    DrMAB-957 Human Anti-HMGB1 Recombinant Antibody (clone Giby-1-4), Biotin ELISA, WB Human IgG
    MOB-0839CT Recombinant Mouse anti-Human HMGB1 Monoclonal antibody (19N10B7) ELISA, FC, ICC/IF, IHC-P, WB
    VS3-WK1655 Recombinant Mouse Anti-HMGB1 Detection Antibody (clone 1G1) ELISA Mouse IgG2b
    VS-0824-CJ6 Human Anti-HMGB1 Recombinant Antibody (clone G16) ELISA Human IgG

    Customer Reviews and Q&As

    Customer Review Q&As

    Submit a review or a question


    Consistent Results in Diagnostic Development
    This antibody offers exceptional consistency, crucial for diagnostic development. It provides reliable and reproducible results in detecting HMGB1, significantly improving diagnostic accuracy and efficiency.

    Enhanced Accuracy in Cancer Research
    The Mouse Anti-HMGB1 Recombinant Antibody from Creative Biolabs excels in cancer research. Its high sensitivity allows precise detection of HMGB1, enhancing the understanding of tumor biology and therapeutic targets.

    Popular products with customers

    Figure 3 Anti-Human EPCAM Antibody (TAB-106) in DB

    Anti-Human EPCAM Recombinant Antibody (Adecatumumab) (CAT# TAB-106)
    Application: FC, IHC, FuncS, Inhib, Cyt

    Figure 1 Human TWEAK receptor Therapeutic Antibody (TAB-178) in ELISA

    Anti-Human TWEAK receptor Recombinant Antibody (TAB-178) (CAT# TAB-178)
    Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

    Figure 3 Anti-GPC3 Antibody (TAB-H14) in ELISA

    Anti-Human GPC3 Recombinant Antibody (Codrituzumab) (CAT# TAB-H14)
    Application: FuncS, IF, Neut, ELISA, FC, IP, ICC

    Figure 2 Anti-Human CD252 Antibody (TAB-223) in WB

    Anti-Human CD252 Recombinant Antibody (TAB-223) (CAT# TAB-223)
    Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

    Figure 3 Anti-Human IL17A Recombinant Antibody (TAB-H08) in DB

    Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08) (CAT# TAB-H08)
    Application: ELISA, FC, IP, FuncS, IF, Neut, WB

    Figure 2 Human IL31 Recombinant Antibody (AFC-409CL) in ELISA

    Afuco™ Anti-Human IL31 ADCC Recombinant Antibody (BMS-981164), ADCC Enhanced (CAT# AFC-409CL)
    Application:

    Figure 2 Recombinant Anti-1,3-Beta-glucan Antibody (MOB-0228MC) in HPLC

    Recombinant Anti-1,3-Beta-glucan Antibody (CAT# MOB-0228MC)
    Application: ELISA, WB, IP, FuncS

    Figure 1 Recombinant Human Anti-DENV E proteins Antibody (PABL-067) in SDS-PAGE

    Recombinant Human Anti-DENV E proteins Antibody (5J7) (CAT# PABL-067)
    Application: ELISA, Neut, FuncS

    Figure 4 Human Anti-JAG1 Recombinant Antibody (PABL-312) in DB

    Human Anti-JAG1 Recombinant Antibody (PABL-312) (CAT# PABL-312)
    Application: IB, IF, IHC

    Figure 3 Mouse Anti-Human FCGR2B Antibody (TAB-036WM) in ELISA

    Mouse Anti-FCGR2B Recombinant Antibody (TAB-036WM) (CAT# TAB-036WM)
    Application: ELISA, FC, Inhib

    Figure 2 Anti-Human PLAUR Recombinant Antibody (TAB-238CQ) in HPLC

    Anti-Human PLAUR Recombinant Antibody (2.19.2) (CAT# TAB-238CQ)
    Application: Inhib, WB

    Figure 2 Anti-Human SNCA Antibody (TAB-0748CLV) in ELISA

    Mouse Anti-SNCA Recombinant Antibody (TAB-0748CLV) (CAT# TAB-0748CLV)
    Application: ELISA, DB, WB

    Figure 5 Mouse Anti-HIV-1 p24 Recombinant Antibody (MRO-928CQ) in ELISA

    Mouse Anti-HIV-1 p24 Recombinant Antibody (MRO-928CQ) (CAT# MRO-928CQ)
    Application: ELISA

    Figure 2 Human Anti-RSV F Recombinant Antibody (MRO-878LC) in ELISA

    Human Anti-RSV F Recombinant Antibody (MRO-878LC) (CAT# MRO-878LC)
    Application: ELISA, Neut

    Figure 4 Anti-Human CD47 Antibody (HPAB-0008-FY) in HPLC

    Human Anti-CD47 Recombinant Antibody (HPAB-0008-FY) (CAT# HPAB-0008-FY)
    Application: ELISA, PD, Activ, PK, Stim

    Figure 2 Human Anti-CA19-9 Recombinant Antibody; Fab Fragment (HPAB-0038-WJ-F(E)) in HPLC

    Human Anti-CA19-9 Recombinant Antibody Fab Fragment (HPAB-0038-WJ-F(E)) (CAT# HPAB-0038-WJ-F(E))
    Application: ELISA

    Figure 2 Anti-TMEM30A Recombinant Antibody (PABL-712CQ) in HPLC

    Human Anti-TMEM30A Recombinant Antibody (PABL-712CQ) (CAT# PABL-712CQ)
    Application: ELISA, FC

    Figure 2 Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) in HPLC

    Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) (CAT# HPAB-N0094-YC)
    Application: Neut, WB

    Figure 3 Mouse Anti-Human MSLN Antibody (HPAB-0886-FY) in WB

    Mouse Anti-MSLN Recombinant Antibody (HPAB-0886-FY) (CAT# HPAB-0886-FY)
    Application: FC

    Figure 4 Mouse Anti-ACTA2 Antibody (ZG-1036F) in IHC

    Mouse Anti-ACTA2 Recombinant Antibody (clone HHF35) (CAT# ZG-1036F)
    Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB

    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare