Mouse Anti-HMMR Recombinant Antibody (clone 16E10); scFv Fragment (CAT#: HPAB-0061-YJ-S(P))
This product is a recombinant mouse antagonist scFv that recognizes human RHAMM (receptor for hyaluronic acid mediated motility). Mab 16E10 is able to inhibit the binding of HA to RHAMM and is interfering with ras-mediated signaling. It can be used as therapeutics for the treatment of proliferative diseases.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to centrosome & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43926/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to centrosome & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/43926/if_selected.jpg
Figure 2 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/61524/1723_D6_28_cr57eab4e82b568_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/61524/1723_D6_28_cr57eab4e82b568_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2433/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2433/if_selected.jpg
Figure 4 Testis
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2433/6892_A_6_6.jpg
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2433/6892_A_6_6.jpg
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000072571-HMMR
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000072571-HMMR
Specifications
- Immunogen
- Recombinant human RHAMM protein
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human HMMR
- Species Reactivity
- Human
- Clone
- 16E10
- Applications
- IA
- Related Disease
- Inflammatory Bowel Disease, Cancer, Arthritis, Psoriatics
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Hyaluronan Mediated Motility Receptor; Intracellular Hyaluronic Acid-Binding Protein; Receptor For Hyaluronan-Mediated Motility; IHABP; RHAMM; Hyaluronan-Mediated Motility Receptor (RHAMM); Hyaluronan-Mediated Motility Receptor; CD168 Antigen; CD168; 16E10; MAb 16E10
- Gene ID
- 3161
- UniProt ID
- O75330
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3749z | Mouse Anti-HMMR Recombinant Antibody (clone 22A5) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| MOB-0458CT | Recombinant Mouse anti-Human HMMR Monoclonal antibody (3E7) | FC, ICC/IF, IHC-Fr, IHC-P | |
| HPAB-0061-YJ | Mouse Anti-HMMR Recombinant Antibody (clone 16E10) | IA | Mouse IgG1, κ |
| VS3-XY810 | Mouse Anti-HMMR Recombinant Antibody (clone 2F6B8) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY3382 | Rabbit Anti-HMMR Recombinant Antibody (clone R08-7D4) | WB, IHC-P, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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