Recombinant Mouse Anti-HRV2 Antibody (8F5) (CAT#: FAMAB-0169YC)
Provided is a monoclonal antibody (8F5) that neutralizes human rhinovirus serotype 2. Antibody 8F5 cross-reacts with peptides of the viral capsid protein VP2, which contributeo the neutralizing immunogenic site B in this serotype.
Specific Inquiry
IF
Figure 1 MAbs 8F5 and 3B10 bind to FcRII.
Note the absence ofAlexa 488 staining in cells that do not express FcRII (arrows). Bar, 20 μm.
Baravalle, G., Brabec, M., Snyers, L., Blaas, D., & Fuchs, R. (2004). Human rhinovirus type 2-antibody complexes enter and infect cells via Fc-γ receptor IIB1. Journal of virology, 78(6), 2729-2737.
FC
Figure 2 MAbs 8F5 and 3B10 bind to FcRII.
Cells were analyzed byflow cytometry. One typical experiment out of three is shown. Note that only those cells that express FcRII bound the MAbs.
Baravalle, G., Brabec, M., Snyers, L., Blaas, D., & Fuchs, R. (2004). Human rhinovirus type 2-antibody complexes enter and infect cells via Fc-γ receptor IIB1. Journal of virology, 78(6), 2729-2737.
Specifications
- Immunogen
- Native HRV2 virions
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- HRV2
- Species Reactivity
- HRV2
- Clone
- 8F5
- Applications
- Neutralization
- Related Disease
- HRV2 infection
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- HRV2; Rhinovirus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-512 | Recombinant Anti-HRV2 Antibody | ELISA, WB, IF, FuncS | IgG |
| MHH-512 | Recombinant Human Anti-HRV2 Antibody | WB, IF, FuncS | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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