AbPlus™ Anti-HYOU1 Magnetic Beads (h5F4Ac.2/v17)
CAT#: VS-0424-XY138
The AbPlus Anti-HYOU1 Magnetic Beads (h5F4Ac.2/v17) is an innovative affinity resin which is bound with anti-HYOU1 specific antibody (h5F4Ac.2/v17). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of HYOU1 protein under native and denaturing conditions.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows distinct cytoplasmic positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_9_3.jpg
Normal Tissue
Figure 4 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_2_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (EFO-21)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149428-HYOU1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-HYOU1 specific antibody (h5F4Ac.2/v17)
- Target
- HYOU1
- Target Species
- Human
- Antibody Clone
- h5F4Ac.2/v17
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. Alternative splicing results in multiple transcript variants.
- Alternative Names
- Hypoxia Up-Regulated 1; 170 KDa Glucose-Regulated Protein; 150 KDa Oxygen-Regulated Protein; GRP-170; ORP-150; Grp170
- Gene ID
- 10525
- UniProt ID
- Q9Y4L1
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "HYOU1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1502CT | Recombinant Mouse anti-Human HYOU1 Monoclonal antibody (EML1057) | IHC-P, WB | |
| HPAB-AP850-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG1) | FuncS | Human IgG1 |
| HPAB-AP851-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG2) | FuncS | Human IgG2 |
| HPAB-AP852-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG3) | FuncS | Human IgG3 |
| HPAB-AP853-YC | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG4) | FuncS | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1719 | Rabbit Anti-HYOU1 Recombinant Antibody (clone DS1719AB) | WB, IHC, ICC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-DJB | Mouse Anti-HYOU1 Recombinant Antibody (HPAB-0007-DJB) | ELISA, Apop, WB, FC, FuncS | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-DJB-S(P) | Mouse Anti-HYOU1 Recombinant Antibody; scFv Fragment (HPAB-0007-DJB-S(P)) | ELISA, Apop | Mouse scFv |
| HPAB-0735-CN-S(P) | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17); scFv Fragment | WB, ELISA, IP, FC | Humanized scFv |
| HPAB-AP669-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 3B6.1); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| HPAB-AP670-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 6A4.28); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| HPAB-AP671-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 9A6.2); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0007-DJB-F(E) | Mouse Anti-HYOU1 Recombinant Antibody; Fab Fragment (HPAB-0007-DJB-F(E)) | ELISA, Apop | Mouse Fab |
| HPAB-AP850-YC-F(E) | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG1); Fab Fragment | Apop, CDC, ELISA, WB | Human Fab |
| HPAB-AP851-YC-F(E) | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG2); Fab Fragment | Apop, CDC, ELISA, WB | Human Fab |
| HPAB-AP852-YC-F(E) | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG3); Fab Fragment | Apop, CDC, ELISA, WB | Human Fab |
| HPAB-AP853-YC-F(E) | Human Anti-HYOU1 Recombinant Antibody (clone c5F4-hIgG4); Fab Fragment | Apop, CDC, ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1072 | AbPlus™ Anti-HYOU1 Magnetic Beads (VS-0724-YC1072) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC131 | Mouse Anti-HYOU1 Recombinant Antibody Hexamer (VS-0924-YC131), CDC Enhanced | Apop, CDC, FC | Antibody hexamer |
| VS-0924-YC132 | Human Anti-HYOU1 Recombinant Antibody Hexamer (VS-0924-YC132), CDC Enhanced | CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3364 | Anti-HYOU1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3365 | Anti-Mouse HYOU1 Immunohistochemistry Kit | IHC |
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