This product is a recombinant mouse antibody clone FluBI, which specifically binds to IAV HA.
Figure 1 MDCK cells were infected with A/WSN/33 and labelled with 35S-cysteine/methionine for 4 h before lysis.
Lysates were immunoprecipitated with monoclonal anti-M2, FluBI serum (FluBI), or serum from uninfected (nms) or A/WSN/33-infected mice (Anti-WSN).
Dougan, S. K., Ashour, J., Karssemeijer, R. A., Popp, M. W., Avalos, A. M., Barisa, M., Altenburg, A. F., Ingram, J. R., Cragnolini, J. J., Guo, C., Alt, F. W., Jaenisch, R., & Ploegh, H. L. (2013). Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus. Nature, 503(7476), 406–409.
Figure 2 Influenza virus targets B cells for infection through the BCR.
CD40-activated OBI or FluBI B cells were incubated with HA-SRTAlexa 647 virus for 30 min on ice and analysed by cytofluorometry.
Dougan, S. K., Ashour, J., Karssemeijer, R. A., Popp, M. W., Avalos, A. M., Barisa, M., Altenburg, A. F., Ingram, J. R., Cragnolini, J. J., Guo, C., Alt, F. W., Jaenisch, R., & Ploegh, H. L. (2014). Antigen-specific B-cell receptor sensitizes B cells to iction by influenza virus. Nature, 503(7476), 406–409.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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