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    Human Anti-IAV HA Vaccinal Antibody (VS-0625-XY51)

    CAT#: VS-0625-XY51

    Designed for specific recognition of IAV hemagglutinin head, this antibody enables ELISA, BLI, and Neut applications. Fc segment engineering drives vaccine-like immune activation while boosting antiviral performance against influenza.

    Specifications

    • Target
    • IAV HA
    • Host Animal
    • Human
    • Applications
    • ELISA; BLI; Neut
    • Specificity
    • IAV HA
    • Species Reactivity
    • IAV
    • Type
    • Human IgG
    • Purity
    • >95%, determined by SDS-PAGE
    • Purification
    • Protein A purified
    • Format
    • Liquid
    • Buffer
    • PBS, pH 7.4
    • Preservative
    • No preservatives
    • Storage
    • Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

    Target

    • Introduction
    • Hemagglutinin are the receptor-binding and membrane fusion glycoproteins of influenza viruses. They recognize sialic acid-containing, cell-surface glycoconjugates as receptors but have limited affinity for them, and, as a consequence, virus attachment to cells requires their interaction with several virus HAs. Receptor-bound virus is transferred into endosomes where membrane fusion by HAs is activated at pH between 5 and 6.5, depending on the strain of virus. Fusion activity requires extensive rearrangements in HA conformation that include extrusion of a buried "fusion peptide" to connect with the endosomal membrane, form a bridge to the virus membrane, and eventually bring both membranes close together.
    • Related Disease
    • Influenza
    • Alternative Names
    • Influenza virus Hemagglutinin
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    Downloadable Resources

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    Datasheet

    Datasheet - VS-0625-XY51.pdf

    MSDS

    MSDS - VS-0625-XY51.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Recommended Dilution Buffer

    • CAT
    • Product Name

    Secondary Antibody

    • CAT
    • Product Name

    Isotype Control

    • CAT
    • Product Name

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