Human Anti-IAV HA Vaccinal Antibody (VS-0625-XY52)
CAT#: VS-0625-XY52
Tailored to bind IAV hemagglutinin head, this vaccinal antibody is suitable for ELISA, BLI, and neutralization tests. Fc modification triggers vaccine-like effects and augments antiviral potency to inhibit viral entry.
Specifications
- Target
- IAV HA
- Host Animal
- Human
- Applications
- ELISA; BLI; Neut
- Specificity
- IAV HA
- Species Reactivity
- IAV
- Type
- Human IgG
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Epitope
- Influenza virus hemagglutinin head domain
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Hemagglutinin are the receptor-binding and membrane fusion glycoproteins of influenza viruses. They recognize sialic acid-containing, cell-surface glycoconjugates as receptors but have limited affinity for them, and, as a consequence, virus attachment to cells requires their interaction with several virus HAs. Receptor-bound virus is transferred into endosomes where membrane fusion by HAs is activated at pH between 5 and 6.5, depending on the strain of virus. Fusion activity requires extensive rearrangements in HA conformation that include extrusion of a buried "fusion peptide" to connect with the endosomal membrane, form a bridge to the virus membrane, and eventually bring both membranes close together.
- Related Disease
- Influenza
- Alternative Names
- Influenza virus Hemagglutinin
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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