Rabbit Anti-ICAM3 Recombinant Antibody (VS13-YC564) (CAT#: VS13-YC564)
The Rabbit Anti-ICAM3 Recombinant Antibody is specific for human and rat ICAM3. ICAM3 is a member of the intercellular adhesion molecule (ICAM) family. It functions as an adhesion molecule and a potent signalling molecule. The anti-ICAM3 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunoprecipitation (1/20).
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg
Figure 2 IHC staining of human bone marrow
(High expression. RNA expression: 206.5 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg
(High expression. RNA expression: 206.5 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg
Figure 3 IHC staining of human cerebral cortex
(Low expression. RNA expression: 6.4 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg
(Low expression. RNA expression: 6.4 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg
Figure 4 Colon
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg
Figure 6 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
Specifications
- Immunogen
- Recombinant human ICAM3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Rat ICAM3
- Species Reactivity
- Human, Rat
- Applications
- WB, IHC-P, IP
- Conjugate
- NONE
- Related Disease
- Colon Carcinoma In Situ and Intestine Carcinoma In Situ
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- Intercellular Adhesion Molecule 3
- Gene ID
- 3385
- UniProt ID
- P32942
- Long Name
- Intercellular Adhesion Molecule 3
- Sequence Similarities
- Belongs to the immunoglobulin superfamily. ICAM family.
- Cellular Localization
- Membrane
- Protein Refseq
- NP_001307534.1; NP_001307535.1; NP_001307537.1; NP_001382303.1; NP_001382304.1
- Function
- ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-534 | Recombinant Anti-human ICAM3 Antibody | WB, FC, FuncS | IgG |
| HPAB-1602WJ | Mouse Anti-ICAM3 Recombinant Antibody (clone ICR-8.1) | ELISA, WB, FC | Mouse IgG1, κ |
| HPAB-1603WJ | Human Anti-ICAM3 Recombinant Antibody (clone huICR-8.1) | ELISA, WB, FC | Human IgG1, κ |
| HPAB-1604WJ | Mouse Anti-ICAM3 Recombinant Antibody (clone ICR-1.1) | ELISA, WB, FC | Mouse IgG1, κ |
| HPAB-1605WJ | Human Anti-ICAM3 Recombinant Antibody (clone huICR-1.1) | ELISA, WB, FC | Human IgG1, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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