Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0073-WJ-F(E)) (CAT#: HPAB-0073-WJ-F(E))
This product is a recombinant human antibody Fab Fragment that recognizes ICOS. The antibody was purified by affinity chromatography. It can be used for ELISA and other applications.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg
Figure 2 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg
Figure 5 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg
Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human ICOS
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Graft versus host disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ICOS; inducible T-cell co-stimulator; AILIM; CD278; CVID1; inducible T-cell costimulator; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule
- Gene ID
- 29851
- UniProt ID
- Q53QY6
Related Resources
Primary Immunodeficiency
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ICOS"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1124z | Mouse Anti-ICOS Recombinant Antibody (clone 41C5) | FC, IHC, IP, FuncS | Mouse IgG1, κ |
| HPAB-0109-CN | Hamster Anti-ICOS Recombinant Antibody (HPAB-0109-CN) | ELISA, FC, IHC | Hamster IgG |
| HPAB-0110-CN | Hamster Anti-ICOS Recombinant Antibody (HPAB-0110-CN) | ELISA, FC, IHC | Hamster IgG |
| HPAB-0111-CN | Human Anti-ICOS Recombinant Antibody (HPAB-0111-CN) | ELISA, FC, IHC | Humanized IgG |
| HPAB-0022LY | Human Anti-ICOS Recombinant Antibody (HPAB-0022LY) | Inhib, WB, IHC, ELISA | Human IgG |
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