Anti-ICOS Immunohistochemistry Kit
CAT#: VS-0525-XY3374
This ICOS IHC kit offers reliable reagents for the efficient detection of ICOS in tissue samples. It is optimized for both paraffin and frozen tissue sections, ensuring reproducibility. The optimized protocol guarantees high specificity with minimal background interference.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg
Subcellular Location
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg
Normal Tissue
Figure 5 Tonsil
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
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Specifications
- Application
- IHC
- Size
- 50 Tests
- Species Reactivity
- Human
- Target
- ICOS
- Primary Antibody
- Rabbit Anti-ICOS Antibody
- Secondary Antibody
- Goat anti-Rabbit Antibody, HRP
- Sample Type
- FFPE tissue; Frozen section tissue
- Kit Storage
- All reagents should be kept at 2-8°C. The kit remains stable for up to 6 months after arrival.
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Related Diseases
Primary Immunodeficiency
Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-128CT | Mouse Anti-ICOS Recombinant Antibody (TAB-128CT) | ELISA, WB | Mouse IgG |
| TAB-128CT-S(P) | Mouse Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-128CT-S(P)) | ELISA, WB | Mouse scFv |
| TAB-128CT-F(E) | Mouse Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-128CT-F(E)) | ELISA, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-129CT | Human Anti-ICOS Recombinant Antibody (TAB-129CT) | ELISA, Neut | Human IgG2, κ |
| TAB-129CT-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-129CT-S(P)) | ELISA, Neut | Human scFv |
| TAB-129CT-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-129CT-F(E)) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-941CQ | Mouse Anti-ICOS Recombinant Antibody (clone CBL817) | Neut, FC, CyTOF | Mouse IgG1 |
| NEUT-942CQ | Rat Anti-Icos Recombinant Antibody (clone 7E.17G9) | FC, FuncS, Neut | Rat IgG2b, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-943CQ | Rat Anti-Icos Recombinant Antibody (NEUT-943CQ) | Block, FC | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1727 | Rabbit Anti-ICOS Recombinant Antibody (clone DS1727AB) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0109-CN | Hamster Anti-ICOS Recombinant Antibody (HPAB-0109-CN) | ELISA, FC, IHC | Hamster IgG |
| HPAB-0073-WJ | Human Anti-ICOS Recombinant Antibody (HPAB-0073-WJ) | ELISA, IHC, Inhib, FC | Human IgG |
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| HPAB-0052-YJ | Human Anti-ICOS Recombinant Antibody (clone JMab-136) | ELISA | Human IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0073-WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0073-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0022LY-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0022LY-S(P)) | WB | Human scFv |
| HPAB-0052-YJ-S(P) | Human Anti-ICOS Recombinant Antibody (clone JMab-136); scFv Fragment | ELISA | Human scFv |
| HPAB-1261WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-1261WJ-S(P)) | Neut, ELISA | Human scFv |
| HPAB-1262WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-1262WJ-S(P)) | Neut, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0073-WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0073-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0022LY-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0022LY-F(E)) | WB | Human Fab |
| HPAB-0052-YJ-F(E) | Human Anti-ICOS Recombinant Antibody (clone JMab-136); Fab Fragment | ELISA | Human Fab |
| HPAB-1261WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1261WJ-F(E)) | Neut, ELISA | Human Fab |
| HPAB-1262WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1262WJ-F(E)) | Neut, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1522 | Human Anti-ICOS Recombinant Antibody (clone JTX-2011) | ELISA, FC | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY123 | CytoStream™ Mouse Anti-ICOS Recombinant Antibody (VS-0225-XY123) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY63 | Human Anti-ICOS (clone JMab-136) scFv-Fc Chimera | ELISA, FC | Human IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC522 | Recombinant Anti-ICOS Vesicular Antibody, EV Displayed (VS-0425-YC522) | ELISA, FC, Neut, Cell-uptake |
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