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    Human Anti-ICOS Recombinant Antibody (clone JTX-2011) (CAT#: VS3-WK1522)

    This product is a human monoclonal antibody that recognizes ICOS.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line HEL
    Figure 1 IF staining of human cell line HEL
    (Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg
    Figure 2 IHC staining of human tonsil
    Figure 2 IHC staining of human tonsil
    (Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg
    Figure 3 IF staining of human cell line U-2 OS
    Figure 3 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg
    Normal Tissue
    Figure 4 Lymph node
    Figure 4 Lymph node
    (Germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg
    Figure 5 Tonsil
    Figure 5 Tonsil
    (Germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg
    RNA Expression
    Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
    Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS
    Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
    Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS

    Specifications

    • Host Species
    • Human
    • Derivation
    • Humanized
    • Type
    • Humanized IgG1
    • Specificity
    • Human ICOS
    • Species Reactivity
    • Human
    • Clone
    • JTX-2011
    • Applications
    • ELISA, FC
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Affinity purified
    • Purity
    • >95% as determined by SDS-PAGE
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS (pH 7.4)
    • Storage
    • Store at -20°C for 1 year.Avoid freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • This antibody has been tested for use in ELISA (1:5000-10000) and Flow Cytometry.

    Target

    • Alternative Names
    • AILIM; CD278; CVID1
    • Long Name
    • Inducible T cell costimulator

    Recommended Products

    Secondary Antibody

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ICOS"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Mouse Antibody Products Human Antibody Products Neutralizing Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1124z Mouse Anti-ICOS Recombinant Antibody (clone 41C5) FC, IHC, IP, FuncS Mouse IgG1, κ
    MOB-2311MZ Recombinant Mouse Anti-Human ICOS Antibody (clone 26-525), APC-Conjugated FC Mouse antibody
    HPAB-0073-WJ Human Anti-ICOS Recombinant Antibody (HPAB-0073-WJ) ELISA, IHC, Inhib, FC Human IgG
    FN-184CQ Hamster Anti-ICOS Recombinant Antibody (clone C398.4A) FC, FuncS Hamster IgG
    FN-225CQ Mouse Anti-ICOS Recombinant Antibody (clone ISA-3) FC, FuncS, TCA Mouse IgG1, κ

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