Recombinant Anti-IFNA2 Eliminating Antibody, pH-Sensitive (3B7 var.)
CAT#: VS-0625-YC152
The anti-IFNA2 eliminating antibody is an engineered pH-sensitive antibody against human IFNA2. IFNA2 is a viral-response cytokine reducing cold symptoms, part of the interferon gene cluster. The antibody has a novel IFNA2-sweeping activity in vivo, which selectively eliminatesthe soluble IFNA2 from plasma. Compared to conventional antibody, the mAb exerted in vivo efficacy by simultaneously engineering both pH-dependent antigen binding, to mimic the pH-dependent receptor-ligand binding of such endocytic receptors, and increased FcRn binding affinity at neutral pH, to mimic the cell-bound form of the receptors.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188379-IFNA2
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Specifications
- Immunogen
- Recombinant human IFNAR2 protein
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human IFNA2
- Species Reactivity
- Human
- Clone
- 3B7 var.
- Applications
- Antigen-Sweeping In Vivo.
Product Property
- Purification
- Protein A/G purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS only
- Preservative
- None
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1175z | Mouse Anti-IFNA2 Recombinant Antibody (clone 33D4) | ELISA, FC, ICC, IF | Mouse IgG1, κ |
| MOB-2029MZ | Recombinant Mouse Anti-Human IFNA2 Antibody (clone O38) | ELISA, ELISA, WB | Mouse antibody |
| HPAB-0116-LSX | Mouse Anti-IFNA2 Recombinant Antibody (clone 3B7) | WB, FC | Mouse IgG2a |
| HPAB-0117-LSX | Mouse Anti-IFNA2 Recombinant Antibody (clone 1F3) | WB | Mouse IgG2a |
| HPAB-1731-FY | Mouse Anti-IFNA2 Recombinant Antibody (clone ScFv17) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0278MZ | Chicken Anti-Interferon α2 Polyclonal IgY | WB, Indirect ELISA | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-965CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone MMHA-11) | ELISA, Neut | Mouse IgG1 |
| NEUT-1065CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone 2-48) | ELISA, IHC-Fr, Neut, WB | Mouse IgG1 |
| NEUT-1066CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone MMHA-1) | ELISA, Neut | Mouse IgG1, κ |
| NEUT-1067CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone CBL230) | ELISA, Neut | Mouse IgG1 |
| NEUT-1068CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone CBL1025) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-973CQ | Mouse Anti-IFNA2 Recombinant Antibody (clone N39) | ELISA, Block, WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0116-LSX-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone 3B7); scFv Fragment | ELISA, EMSA | Mouse scFv |
| HPAB-0117-LSX-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1F3); scFv Fragment | ELISA, EMSA | Mouse scFv |
| HPAB-0118-LSX-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1D3); scFv Fragment | ELISA, EMSA | Mouse scFv |
| HPAB-1731-FY-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone ScFv17); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0116-LSX-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone 3B7); Fab Fragment | ELISA, EMSA | Mouse Fab |
| HPAB-0117-LSX-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1F3); Fab Fragment | ELISA, EMSA | Mouse Fab |
| HPAB-0118-LSX-F(E) | Mouse Anti-IFNA2 Recombinant Antibody (clone 1D3); Fab Fragment | ELISA, EMSA | Mouse Fab |
| HPAB-1731-FY-S(P) | Mouse Anti-IFNA2 Recombinant Antibody (clone ScFv17); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-040CN | Human Anti-IFNA2 Recombinant Antibody (NS-040CN) | ELISA, WB, FC, ADCC | Human IgG |
| NS-040CN-F(E) | Human Anti-IFNA2 Recombinant Antibody; Fab Fragment (NS-040CN-F(E)) | ELISA, WB, FC | Human Fab |
| NS-040CN-S(P) | Human Anti-IFNA2 Recombinant Antibody; scFv Fragment (NS-040CN-S(P)) | ELISA, WB, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY166 | Mouse Anti-IFNA2 (clone ScFv17) scFv-Fc Chimera | ELISA, IHC, WB | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3405 | Anti-IFNA2 Immunohistochemistry Kit | IHC |
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