CytoStream™ Rabbit Anti-IFNGR1 Recombinant Antibody (VS13-YC567) (CAT#: VS13-YC567)
The CytoStream™ Rabbit Anti-IFNGR1 Recombinant Antibody is specific for human IFNGR1. IFNGR1 participates in the immune response with susceptibility related to infections like Helicobacter pylori due to genetic variations affecting interferon receptor expression. The anti-IFNGR1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29213/273_A10_2_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29213/273_A10_2_selected.jpg
Figure 2 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong membranous positivity in cells in red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_9_4_selected.jpg
(Immunohistochemical staining of human spleen shows strong membranous positivity in cells in red pulp.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_9_4_selected.jpg
Figure 3 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong membranous and cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25889/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows strong membranous and cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25889/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_B_8_5.jpg
Figure 5 Lung
(Macrophages Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_A_1_4.jpg
(Macrophages Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63871/148756_A_1_4.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000027697-IFNGR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000027697-IFNGR1
Specifications
- Immunogen
- Recombinant human IFNGR1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IFNGR1
- Species Reactivity
- Human
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Mycobacterial disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Interferon Gamma Receptor 1
- Gene ID
- 3459
- UniProt ID
- P15260
- Long Name
- Interferon Gamma Receptor 1
- Sequence Similarities
- Belongs to the type II cytokine receptor family.
- Cellular Localization
- Cell membrane; Membrane
- Protein Refseq
- XP_006715533.1; XP_011534095.1; XP_011534096.1; XP_047274682.1; XP_054211301.1
- Function
- Receptor subunit for interferon gamma/INFG that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.
Recommended Products
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Isotype Control
Related Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-080 | Mouse Anti-IFNGR1 Recombinant Antibody (clone A6) | Neut | Mouse IgG |
| FAMAB-0193CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38) | ELISA, RIA | Mouse IgG |
| FAMAB-0194CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99) | ELISA, RIA | Mouse IgG |
| FAMAB-1381CQ | Rabbit Anti-IFNGR1 Recombinant Antibody (clone GR20) | Block, Neut, FC | Rabbit IgG |
| VS3-FY729 | Recombinant Mouse Anti-IFNGR1 Antibody (clone 3B2D4) | ELISA, ICC, FC | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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