Afuco™ Anti-IgE Fc ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-886)
CAT#: AFC-TAB-886
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human IgE Fc. It is a humanized monoclonal antibody as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E (IgE) and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC
- Conjugate
- Unconjugated
- Generic Name
- Talizumab
- Related Disease
- Peanut allergy (severe)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IgE Fc; IgE; Immunoglobulin E; Immunoglobulin E Fc
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Biosimilar Overview
Please refer to Talizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Talizumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Talizumab"
Anti-Human IgE Fc Recombinant Antibody (Talizumab)Recombinant humanized (from mouse) antibody expressed in CHO binding to human IgE Fc. Talizumab is a humanized monoclonal antibody as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E (IgE) and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils.
See other products for "IgE Fc"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1378-VHH | Recombinant Anti-Human IgE Fc VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| PABC-586 | Recombinant Llama Anti-IgE Fc Single Domain Antibody (PABC-586) | ELISA, FC, SPR | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-886 | Anti-Human IgE Fc Recombinant Antibody (Talizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-230 | Human Anti-IgE Fc Recombinant Antibody (PABL-230) | ELISA, WB, Neut, FuncS | Human IgG |
| PABC-341 | Human Anti-IgE Fc Recombinant Antibody (PABC-341) | FC | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-230 | Human Anti-IgE Fc Recombinant Antibody scFv Fragment (PSBL-230) | ELISA, WB, Neut, FuncS | Human scFv |
| PSBC-341 | Human Anti-IgE Fc Recombinant Antibody scFv Fragment (PSBC-341) | FC, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-230 | Human Anti-IgE Fc Recombinant Antibody Fab Fragment (PFBL-230) | ELISA, WB, Neut, FuncS | Human Fab |
| PFBC-341 | Human Anti-IgE Fc Recombinant Antibody Fab Fragment (PFBC-341) | FC, Inhib | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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