Afuco™ Anti-IgE Fc ADCC Recombinant Antibody (Talizumab), ADCC Enhanced (CAT#: AFC-TAB-886)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human IgE Fc. Talizumab is a humanized monoclonal antibody as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E (IgE) and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils.


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Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Talizumab
  • Applications
  • IF, IP, Neut, FuncS, ELISA, FC
  • Conjugate
  • Unconjugated
  • Generic Name
  • Talizumab
  • Related Disease
  • Peanut allergy (severe)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Talizumab; 380610-22-0; TNX-901; Hu901; CGP-5101; CL-5I; TNX-901; IgE Fc; IgE; Immunoglobulin E; Immunoglobulin E Fc

Related Resources

  • Biosimilar Overview
Please refer to Talizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Talizumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Talizumab"

Anti-Human IgE Fc Recombinant Antibody (Talizumab)
Recombinant humanized (from mouse) antibody expressed in CHO binding to human IgE Fc. Talizumab is a humanized monoclonal antibody as a new-concept therapeutic for allergic diseases. The unique anti-IgE antibody was designed to target immunoglobulin E (IgE) and IgE-expressing B lymphocytes specifically, without binding to IgE already bound by the high affinity IgE receptors on mast cells and basophils.

See other products for "IgE Fc"

Single-domain Antibody

CAT Product Name Application Type
NAB-1378-VHH Recombinant Anti-Human IgE Fc VHH Single Domain Antibody IHC, IP, FC, Neut, FUNC Llama VHH
PABC-586 Recombinant Llama Anti-IgE Fc Single Domain Antibody (026) ELISA, FC, SPR Llama VHH

Humanized Antibody

CAT Product Name Application Type
TAB-886 Anti-Human IgE Fc Recombinant Antibody (Talizumab) IF, IP, Neut, FuncS, ELISA, FC, ICC IgG1

Recombinant Antibody

CAT Product Name Application Type
PABL-230 Human Anti-IgE Fc Recombinant Antibody (clone MEDI4212) ELISA, WB, Neut, FuncS Human IgG
PABC-341 Human Anti-IgE Fc Recombinant Antibody (clone 8D6) FC Human IgG

scFv Fragment Antibody

Fab Fragment Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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