Recombinant Llama Anti-IgE Fc Single Domain Antibody (026) (CAT#: PABC-586)
This product is a recombinant Llama antibody that can recognize IgE-Fc. 026, a sdab that was selected against IgE.
Specific Inquiry
SPR
Figure 1 The affinity of the 026 antiIgE binding to immobilized IgE Fc was assessed by surface plasmon resonance.
Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B., Miehe, M., ... & Möbs, C. (2018). Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. Nature communications, 9(1), 7.
ELISA
Figure 2 Immunoreactivity of the 026 sdab to recombinant IgE Fc was assessed by ELISA.
Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B., Miehe, M., ... & Möbs, C. (2018). Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. Nature communications, 9(1), 7.
Specifications
- Host Species
- Llama
- Type
- Llama VHH
- Specificity
- Human IgE-Fc
- Species Reactivity
- Human
- Clone
- 026
- Applications
- ELISA, FC, SPR
- Related Disease
- Allergic diseases
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry and Surface Plasmon Resonance. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- IgE-Fc; Immunoglobulin E; Fc
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IgE Fc"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1378-VHH | Recombinant Anti-Human IgE Fc VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-886 | Anti-Human IgE Fc Recombinant Antibody (Talizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-230 | Human Anti-IgE Fc Recombinant Antibody (clone MEDI4212) | ELISA, WB, Neut, FuncS | Human IgG |
| PABC-341 | Human Anti-IgE Fc Recombinant Antibody (clone 8D6) | FC | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-230 | Human Anti-IgE Fc Recombinant Antibody (clone MEDI4212); scFv Fragment | ELISA, WB, Neut, FuncS | Human scFv |
| PSBC-341 | Human Anti-IgE Fc Recombinant Antibody (clone 8D6); scFv Fragment | FC, Inhib | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-230 | Human Anti-IgE Fc Recombinant Antibody (clone MEDI4212); Fab Fragment | ELISA, WB, Neut, FuncS | Human Fab |
| PFBC-341 | Human Anti-IgE Fc Recombinant Antibody (clone 8D6); Fab Fragment | FC, Inhib | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-886 | Afuco™ Anti-IgE Fc ADCC Recombinant Antibody (Talizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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