Recombinant Llama Anti-IgE Fc Single Domain Antibody (PABC-586)
CAT#: PABC-586
This product is a recombinant Llama antibody that can recognize IgE-Fc. 026, a sdab that was selected against IgE.
Published Data
SPR
Figure 1 The affinity of the 026 antiIgE binding to immobilized IgE Fc was assessed by surface plasmon resonance.
Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B., Miehe, M., ... & Möbs, C. (2018). Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. Nature communications, 9(1), 7.
ELISA
Figure 2 Immunoreactivity of the 026 sdab to recombinant IgE Fc was assessed by ELISA.
Jabs, F., Plum, M., Laursen, N. S., Jensen, R. K., Mølgaard, B., Miehe, M., ... & Möbs, C. (2018). Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction. Nature communications, 9(1), 7.
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Specifications
- Host Species
- Llama
- Type
- Llama VHH
- Specificity
- Human IgE-Fc
- Species Reactivity
- Human
- Clone
- PABC-586
- Applications
- ELISA, FC, SPR
- Related Disease
- Allergic diseases
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry and Surface Plasmon Resonance. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- IgE-Fc; Immunoglobulin E; Fc
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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