This product is a recombinant rat antibody that recognizes IgE. The antibody was purified by affinity chromatography. It can be used in ELISA, FC.
Figure 1 Generation and characterization of recombinant neutralizing anti-IgE single-chain Ab construct.
Recombinant plasmids expressing the membrane form of single-chain R1E4 were transiently cotransfected with enhanced GFP (EGFP) plasmid into 293 cells and the ability of the cells to bind to IgE was analyzed by flow cytometry.
Ota, T., Aoki-Ota, M., Duong, B. H., & Nemazee, D. (2020). Suppression of IgE B Cells and IgE Binding to FcεRI by Gene Therapy with Single-Chain Anti-IgE. The Journal of Immunology, 8110-8117.
Figure 2 Effect of in vivo expression of secreted form of chimeric single-chain anti-IgE on markers of IgE expression.
Total serum IgE concentration before treatment (□) and 13 days after treatment (■).
Ota, T., Aoki-Ota, M., Duong, B. H., & Nemazee, D. (2020). Suppression of IgE B Cells and IgE Binding to FcεRI by Gene Therapy with Single-Chain Anti-IgE. The Journal of Immunology, 8110-8117.
Figure 3 Ability of rR1E4 anti-IgE protein to affect the biological responses of IgE+ B cells generated in tissue culture.
IgE levels in culture supernatants on day 4 as measured by ELISA.
Ota, T., Aoki-Ota, M., Duong, B. H., & Nemazee, D. (2020). Suppression of IgE B Cells and IgE Binding to FcεRI by Gene Therapy with Single-Chain Anti-IgE. The Journal of Immunology, 8110-8117.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-034ZJ-S(P) | Anti-Human IgE Recombinant Antibody scFv Fragment (CMAB007) | ELISA | Humanized antibody |
TAB-049ZJ-S(P) | Anti-Human IgE Recombinant Antibody scFv Fragment (IGE009) | ELISA, Inhib, FC | Humanized antibody |
TAB-050ZJ-S(P) | Anti-Human IgE Recombinant Antibody scFv Fragment (IGE026) | ELISA, Inhib, FC | Humanized antibody |
TAB-034ZJ-F(E) | Anti-Human IgE Recombinant Antibody Fab Fragment (CMAB007) | ELISA | Humanized antibody |
TAB-049ZJ-F(E) | Anti-Human IgE Recombinant Antibody Fab Fragment (IGE009) | ELISA, Inhib, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-095ZJ | Anti-Human IgE Therapeutic Single Domain Antibody (TAB-095ZJ) | ELISA, Inhib, FC | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-009LC | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-010LC | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-011LC | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-009LC-1 | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-010LC-1 | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-011LC-1 | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-156LC | Recombinant Anti-Human IgE Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-156LC-1 | Recombinant Anti-Human IgE Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0208CQ-F(E) | Mouse Anti-IgE Recombinant Antibody (clone TES-C21); Fab Fragment | ELISA, Block | Mouse Fab |
HPAB-0209CQ-F(E) | Human Anti-IgE Recombinant Antibody (clone huTES-C21); Fab Fragment | ELISA, Block | Humanized Fab |
HPAB-N0143-YC-F(E) | Human Anti-IgE Recombinant Antibody (clone hu4F11-12); Fab Fragment | ELISA, Inhib | Humanized Fab |
HPAB-0283-YJ-F(E) | Mouse Anti-IgE Recombinant Antibody; Fab Fragment (HPAB-0283-YJ-F(E)) | ELISA, Enzymatic activity | Mouse Fab |
HPAB-1195-FY-S(P) | Human Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-1195-FY-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0283-YJ | Mouse Anti-IgE Recombinant Antibody (HPAB-0283-YJ) | ELISA, Enzymatic activity | Mouse IgG |
HPAB-0521-WJ | Human Anti-IgE Recombinant Antibody (HPAB-0521-WJ) | ELISA | Human IgG1 |
HPAB-1195-FY | Human Anti-IgE Recombinant Antibody (HPAB-1195-FY) | ELISA | Human IgG |
HPAB-1196-FY | Human Anti-IgE Recombinant Antibody (HPAB-1196-FY) | ELISA | Human IgG |
HPAB-1197-FY | Human Anti-IgE Recombinant Antibody (HPAB-1197-FY) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0283-YJ-S(P) | Mouse Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-0283-YJ-S(P)) | ELISA, Enzymatic activity | Mouse scFv |
HPAB-0519-WJ-S(P) | Human Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-0519-WJ-S(P)) | ELISA | Human scFv |
HPAB-0520-WJ-S(P) | Human Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-0520-WJ-S(P)) | ELISA | Human scFv |
HPAB-0521-WJ-S(P) | Human Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-0521-WJ-S(P)) | ELISA | Human scFv |
HPAB-1574WJ-S(P) | Human Anti-IgE Recombinant Antibody; scFv Fragment (clone HuMAE11V1) | ELISA, WB, FC | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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