Human Anti-IgM Recombinant Antibody (clone CB2bG8) (CAT#: HPAB-1287WJ)

This product is a human antibody targeting IgM. This antibody has the capability of inducing remyelination, and diagnostic and therapeutic uses thereof particularly in the central nervous system.


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  • Datasheet
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Dot

Figure 1 DOT-BLOT immunoassays of diffusates from brown rice samples probed with MAb EC6.

Figure 1 DOT-BLOT immunoassays of diffusates from brown rice samples probed with MAb EC6.

Rice grains inoculated with Penicillium sp. XCII.

Dewey, F. M., MacDonald, M. M., & Phillips, S. I. (1989). Development of monoclonal-antibody-ELISA,-DOT-BLOT and-DIP-STICK immunoassays for Humicola lanuginosa in rice. Microbiology, 135(2), 361-374.

ELISA

Figure 2 Ability of MAbs to detect antigens of H. lanuginosa in inoculated grain.

Figure 2 Ability of MAbs to detect antigens of H. lanuginosa in inoculated grain.

Absorbance values are those given by ELISA with diffusates from inoculated and control rough rice grains tested against MAbs from several hybridoma cell lines and against polyclonal antibodies (PAb).

Dewey, F. M., MacDonald, M. M., & Phillips, S. I. (1989). Development of monoclonal-antibody-ELISA,-DOT-BLOT and-DIP-STICK immunoassays for Humicola lanuginosa in rice. Microbiology, 135(2), 361-374.

Inhib

Figure 3 Effect of silica treatment (50 mg) on ET growth rate in BALB/c mice.

Figure 3 Effect of silica treatment (50 mg) on ET growth rate in BALB/c mice.

The results are the mean ±SEM (bars).

Gil, J., Alvarez, R., Viñuela, J. E., de Morales, J. G. R., Bustos, A., Emilio, G., & Subiza, J. L. (1990). Inhibition of in vivo tumor growth by a monoclonal IgM antibody recognizing tumor cell surface carbohydrates. Cancer research, 50(22), 7301-7306.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Human IgM
  • Species Reactivity
  • Human
  • Clone
  • CB2bG8
  • Applications
  • Inhib, Dot, ELISA
  • Related Disease
  • Demyelinating diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The IgM antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Dot blot, Inhibition.

Target

  • Alternative Names
  • Immunoglobulin M; IgM

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Immunotoxin

CAT Product Name Application Type
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Chicken IgY Antibody

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Blocking Antibody

CAT Product Name Application Type
NEUT-373CQ Mouse Anti-IgM Recombinant Antibody (clone M15/8) ELISA, FC, IHC-Fr, IP, Block Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1778 Rabbit Anti-IgM Recombinant Antibody (clone DS1778AB) ICC, IHC, FC, ELISA Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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