Mouse Anti-IL13 Recombinant Antibody (clone MJ2-7) (CAT#: HPAB-0228CQ)
This product is a recombinant mouse antibody that recognizes IL13. MJ2-7 is an effective neutralizer of both NHP IL-13 and native human IL-13. MJ2-7 blocks IL-13 Interaction with IL-13Rα1 and IL-13Rα2.
Specific Inquiry
Neut
Figure 1 A graph depicting the neutralization of NHP IL-13 activity by MJ2-7 (murine; ●) or humanized MJ2-7 v2.11 (○).
NHPIL-13 activity was measured by phos phorylation of STAT6 (y-axis) as a function of antibody con centration (X-axis).
Neut
Figure 2 A graph depicting the neutralization of NHP IL-13 activity by MJ2-7, as measured by inhibition of induction of tenascin production (y-axis) as a function of antibody concentration (X-axis).
Figure 3 A graph depicting binding of MJ2-7 or control antibodies to NHP-IL-13 bound to SIL-13Rα2-Fc coupled to a SPR chip.
FuncS
Figure 4 Show changes in eotaxin levels in concentrated BAL fluid collected from antibody-treated cynomolgus monkeys post-Ascaris challenge relative to control.
Depicts a decrease in eotaxin levels in concentrated BAL fluids from cynomolgus monkeys treated with mAb 13.2—(grey circles) or MJ2-7— (grey triangles) antibodies compared to a control.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IL13
- Species Reactivity
- Human, Non-Human Primate
- Clone
- MJ2-7
- Applications
- ELISA, FC, Neut, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Neutralization and Functional Assay. Please see the Published Data for further information.
Target
Related Resources
Asthma
Inflammatory Bowel Diseases
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone MJ2-7"
See other products for "IL13"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1287z | Mouse Anti-IL13 Recombinant Antibody (clone 39B4) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| PABL-603 | Human Anti-IL13 Recombinant Antibody (clone C836) | Neut | Chimeric (mouse/human) IgG |
| PABL-605 | Human Anti-IL13 Recombinant Antibody (clone H2L6) | ELISA | Humanized IgG |
| PABL-606 | Human Anti-IL13 Recombinant Antibody (clone X836) | WB, ELISA, FuncS | Chimeric (mouse/human) IgG |
| MOB-0781CT | Recombinant Mouse anti-Human IL13 Monoclonal antibody (43227.22) | ELISA, Neut, WB |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-219 | Anti-Human IL13 Recombinant Antibody (Lebrikizumab) | ELISA, Neut, IF, IP, FC, FuncS | IgG4 - kappa |
| TAB-395CL | Human Anti-IL13 Recombinant Antibody (TAB-395CL) | FuncS | Human IgG |
| TAB-043ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (Lc6Hc2) | ELISA | Humanized antibody |
| TAB-044ZJ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (TAB-044ZJ-F(E)) | ELISA, Neut | Humanized Fab |
| TAB-045ZJ-F(E) | Human Anti-IL13 Recombinant Antibody; Fab Fragment (TAB-045ZJ-F(E)) | ELISA, Block | Humanized Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-170 | Human Anti-IL13 Recombinant Antibody (clone CNTO607); Fab Fragment | ELISA, WB, Neut | Human Fab |
| HPAB-0045LY-F(E) | Human Anti-IL13 Recombinant Antibody (clone IMA-026); Fab Fragment | WB | Humanized Fab |
| HPAB-1739-FY-S(P) | Mouse Anti-IL13 Recombinant Antibody (clone mAb13.2); Fab Fragment | Inhib, ELISA | Mouse Fab |
| HPAB-1740-FY-S(P) | Human Anti-IL13 Recombinant Antibody (clone ch13.2); Fab Fragment | Inhib, ELISA | Chimeric (mouse/human) Fab |
| HPAB-1741-FY-S(P) | Human Anti-IL13 Recombinant Antibody (clone h13.2v1); Fab Fragment | Inhib, ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022ZJ | Anti-Human IL-13 Recombinant Antibody (C836) | ELISA | |
| TAB-023ZJ | Mouse Anti-IL13 Recombinant Antibody (TAB-023ZJ) | ELISA, Block | Mouse IgG |
| TAB-022ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (C836) | ELISA | |
| TAB-022ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (C836) | ELISA | |
| TAB-023ZJ-F(E) | Mouse Anti-IL13 Recombinant Antibody; Fab Fragment (TAB-023ZJ-F(E)) | ELISA, Block | Mouse Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-068ZJ | Anti-Human IL-13 Recombinant Antibody (01471/G6) | WB, ELISA, Neut | Human antibody |
| TAB-067ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (CNTO 607) | ELISA, Inhib | Human antibody |
| TAB-068ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (01471/G6) | ELISA, Neut | Human antibody |
| TAB-069ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-069ZJ-S(P)) | ELISA, Neut, FC | Human scFv |
| TAB-070ZJ-S(P) | Human Anti-IL13 Recombinant Antibody; scFv Fragment (TAB-070ZJ-S(P)) | ELISA, Neut, FC | Human scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-094ZJ | Anti-Human IL-13 Recombinant Antibody (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-S(P) | Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
| TAB-094ZJ-F(E) | Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) | ELISA | Chimeric antibody (mouse/human) |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1171CQ | Mouse Anti-IL13 Recombinant Antibody (clone B-B13) | ELISA, ELISPOT, Neut | Mouse IgG1 |
| NEUT-1172CQ | Mouse Anti-IL13 Recombinant Antibody (clone 10X28) | Neut, WB | Mouse IgG1 |
| NEUT-1173CQ | Mouse Anti-IL13 Recombinant Antibody (clone 15H10) | Neut | Mouse IgG2b |
| NEUT-1174CQ | Mouse Anti-IL13 Recombinant Antibody (clone 32116.11) | ELISA, Neut, WB | Mouse IgG1 |
| NEUT-1175CQ | Rat Anti-IL13 Recombinant Antibody (clone 5A2) | Neut | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1790 | Rabbit Anti-IL13 Recombinant Antibody (clone DS1790AB) | WB, ICC, FC, IP | Rabbit IgG |
| MOR-4610 | Rabbit Anti-IL13 Recombinant Antibody (clone TH123DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H05 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-017ML | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
| AFC-TAB-219 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
| AFC-TAB-218 | Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0355-WJ-S(P) | Human Anti-IL13 Recombinant Antibody (clone 13C5.5); scFv Fragment | ELISA | Humanized scFv |
| HPAB-AP106-YC-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-AP106-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP107-YC-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-AP107-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP108-YC-S(P) | Mouse Anti-IL13 Recombinant Antibody; scFv Fragment (HPAB-AP108-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-1739-FY-F(E) | Mouse Anti-IL13 Recombinant Antibody (clone mAb13.2); scFv Fragment | Inhib, ELISA | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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