Human Anti-IL13 Recombinant Antibody (clone huMJ2-7) (CAT#: HPAB-0229CQ)

This product is a recombinant human antibody that recognizes IL13. MJ2-7 is an effective neutralizer of both NHP IL-13 and native human IL-13. MJ2-7 blocks IL-13 Interaction with IL-13Rα1 and IL-13Rα2.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 A graph depicting binding of varying con centrations (0.09-600 nM) of NHPIL-13 to captured hMJ2-7 V2-11 antibody.

Figure 1 A graph depicting binding of varying con centrations (0.09-600 nM) of NHPIL-13 to captured hMJ2-7 V2-11 antibody.

DB

Figure 2 Dot plots showing humanized MJ2-7-11 (hMJ2-7v.2-11) antibody levels in BAL and serum following intratracheal and intravenous administration.

Figure 2 Dot plots showing humanized MJ2-7-11 (hMJ2-7v.2-11) antibody levels in BAL and serum following intratracheal and intravenous administration.

Animals were treated with human recombinant R110OIL-13, or an equivalent Volume (20 μL) of Saline, intratracheally on days 1, 2, and 3. Humanized MJ2-7v.2-11 antibody was administered on day 0 and 2 hours before each dose of human recombinant R110O IL-13. Depicts the results when the antibody is administered intravenously on day 0 and intraperitoneally on days 1, 2, and 3; or intranasally on days 0, 1, 2, and 3.

FuncS

Figure 3 Show the effect of humanized MJ2-7v.2-11 antibody after intranasal administration of human recombinant R110O IL-13-induced altered lung function.

Figure 3 Show the effect of humanized MJ2-7v.2-11 antibody after intranasal administration of human recombinant R110O IL-13-induced altered lung function.

Shows the changes in lung resistance expressed as change from baseline.


Specifications

  • Host Species
  • Human
  • Derivation
  • Humanized
  • Type
  • Humanized IgG1, κ
  • Specificity
  • Human IL13
  • Species Reactivity
  • Human, Non-Human Primate
  • Clone
  • huMJ2-7
  • Applications
  • ELISA, FC, DB, Neut, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Dot Blot and Functional Assay. Please see the Published Data for further information.

Target

  • Alternative Names
  • Interleukin 13

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone huMJ2-7"

See other products for "IL13"

Chimeric Antibody

CAT Product Name Application Type
TAB-094ZJ Anti-Human IL-13 Recombinant Antibody (167) ELISA Chimeric antibody (mouse/human)
TAB-094ZJ-S(P) Anti-Human IL-13 Recombinant Antibody scFv Fragment (167) ELISA Chimeric antibody (mouse/human)
TAB-094ZJ-F(E) Anti-Human IL-13 Recombinant Antibody Fab Fragment (167) ELISA Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H05 Afuco™ Anti-IL13 ADCC Recombinant Antibody (Anrukinzumab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody
AFC-TAB-017ML Afuco™ Anti-IL13 ADCC Recombinant Antibody (Dectrekumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody
AFC-TAB-219 Afuco™ Anti-IL13 ADCC Recombinant Antibody (Lebrikizumab), ADCC Enhanced ELISA, Neut, IF, IP, FC, FuncS ADCC enhanced antibody
AFC-TAB-218 Afuco™ Anti-IL13 ADCC Recombinant Antibody (Tralokinumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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