Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C) (CAT#: FAMAB-0315JF)

Recombinant monoclonal antibody specially binds to human IL-18R1. 117-10C is a mouse monoclonal antibody that can be useful in neutralizing the cytokine in human conditions associated with high production of IL-18.


Specific Inquiry
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  • Published Data
  • Gene Expression
  • Datasheet
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  • COA
RIA

Figure 1 Inhibition of binding of scFv or 117-10C to the anti-IL-18R by the unlabeled scFv or 117-10C.

Figure 1 Inhibition of binding of scFv or 117-10C to the anti-IL-18R by the unlabeled scFv or 117-10C.

Binding of antibody was expressed as the percentage of binding in the absence of competing unlabeled antibody.


Specifications

  • Immunogen
  • Cells of the Hodgkin's disease-derived cell line L428
  • Host Species
  • Mouse
  • Type
  • Mouse IgM, κ
  • Specificity
  • Human IL-18R1
  • Species Reactivity
  • Human
  • Clone
  • 117-10C
  • Applications
  • ELISA, FuncS
  • Related Disease
  • Autoimmune diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp
  • Function
  • Inhibiting the bioactivity of IL-18

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 117-10C"

See other products for "IL18R1"

Immunotoxin

CAT Product Name Application Type
AGTO-G042E IL-18-PE immunotoxin Cytotoxicity assay, Function study
AGTO-G042D IL-18-DT immunotoxin Cytotoxicity assay, Function study

Humanized Antibody

CAT Product Name Application Type
TAB-211CT Human Anti-IL18R1 Recombinant Antibody (TAB-211CT) FC, ELISA, Ibhibition Humanized antibody
TAB-211CT-S(P) Human Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-211CT-S(P)) FC, ELISA, Ibhibition Humanized scFv
TAB-211CT-F(E) Human Anti-IL18R1 Recombinant Antibody; Fab Fragment (TAB-211CT-F(E)) FC, ELISA, Ibhibition Humanized Fab

Neutralizing Antibody

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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