Mouse Anti-Il1b Recombinant Antibody (clone 9H10) (CAT#: VS-0724-XY84)

• Immunogen
• Purified recombinant murine IL-1β

• Host Species
• Mouse

• Derivation
• Hybridoma

• Type
• Mouse IgG

• Specificity
• Il1b

• Species Reactivity
• Mouse

• Clone
• 9H10

• Applications
• ELISA, BLI, Neut

• Related Disease
• Gastric Cancer; Toxic Shock Syndrome

• Purification
• Protein G affinity purified

• Purity
• >95%, determined by SDS-PAGE

• Format
• Liquid

• Buffer
• PBS

• Preservative
• No preservatives

• Storage
• Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Application Notes
• BLI: The KD value of 9H10 agaisnt Il1b is 0.173 nM.

• Alternative Names
• Il-1b; IL-1beta

• Gene ID
• 16176

• UniProt ID
• P01584

• Cellular Localization
• Cytoplasm; Cytosol; Secreted

• Protein Refseq
• XP_047300131.1; XP_054197785.1; NP_000567.1

• Function
• Potent pro-inflammatory cytokine.
  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
  Promotes Th17 differentiation of T-cells.

Isotype Control

• MOB-065CQ
• Mouse IgG1 Isotype Control Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Secondary Antibody

• 2RD-A1472-YJ
• Goat Anti-Mouse IgG-F(ab')2 Secondary antibody

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