Mouse Anti-Il1b Recombinant Antibody (clone 10G11)

Name: Mouse Anti-Il1b Recombinant Antibody (clone 10G11)
SKU: VS-0724-XY84
Rating: 5 (1 reviews)

CAT#: VS-0724-XY84

This product is a recombinant mouse antibody binding to mouse Il1b (Interleukin 1 beta), which is a member of the interleukin 1 cytokine family. It was obtained by immunizing Balb/c mice with purified recombinant murine IL-1β. It has been tested using ELISA, Bio-layer interferometry and Neutralizaiton assay.

Gene Expression

RNA Expression Figure 1 RNA cell line category: Cell line enhanced.

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125538-IL1B

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Specifications

Immunogen
Purified recombinant murine IL-1β

Host Species
Mouse

Derivation
Hybridoma

Type
Mouse IgG

Specificity
Il1b

Species Reactivity
Mouse

Clone
10G11

Applications
ELISA, BLI, Neut

Related Disease
Gastric Cancer; Toxic Shock Syndrome

Product Property

Purification
Protein G affinity purified

Purity
>95%, determined by SDS-PAGE

Format
Liquid

Buffer
PBS

Preservative
No preservatives

Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Applications

Application Notes
BLI: The KD value of 10G11 agaisnt Il1b is 0.23 nM.

Target

Alternative Names
Il-1b; IL-1beta

Gene ID
16176

UniProt ID
P01584

Cellular Localization
Cytoplasm; Cytosol; Secreted

Protein Refseq
XP_047300131.1; XP_054197785.1; NP_000567.1

Function
Potent pro-inflammatory cytokine.
Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Promotes Th17 differentiation of T-cells.

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(Creative Biolabs Cat# VS-0724-XY84, RRID: AB_3714393)

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Related Diseases

Rheumatoid Arthritis

Maturity Onset Diabetes of the Young

Related Signaling Pathways

TNF Signaling Pathway

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0724-XY84.pdf

MSDS

MSDS - VS-0724-XY84.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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