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    Mouse Anti-Il1b Recombinant Antibody (clone 9H10)

    CAT#: VS-0724-XY84

    This product is a recombinant mouse antibody binding to mouse Il1b (Interleukin 1 beta), which is a member of the interleukin 1 cytokine family. It was obtained by immunizing Balb/c mice with purified recombinant murine IL-1β. It has been tested using ELISA, Bio-layer interferometry and Neutralizaiton assay.

    Gene Expression
    ❮
    Figure 1 RNA cell line category: Cell line enhanced.
    ❯

    Specifications

    • Immunogen
    • Purified recombinant murine IL-1β
    • Host Species
    • Mouse
    • Derivation
    • Hybridoma
    • Type
    • Mouse IgG
    • Specificity
    • Il1b
    • Species Reactivity
    • Mouse
    • Clone
    • 9H10
    • Applications
    • ELISA, BLI, Neut
    • Related Disease
    • Gastric Cancer; Toxic Shock Syndrome

    Product Property

    • Purification
    • Protein G affinity purified
    • Purity
    • >95%, determined by SDS-PAGE
    • Format
    • Liquid
    • Buffer
    • PBS
    • Preservative
    • No preservatives
    • Storage
    • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    Applications

    • Application Notes
    • BLI: The KD value of 9H10 agaisnt Il1b is 0.173 nM.

    Target

    • Alternative Names
    • Il-1b; IL-1beta
    • Cellular Localization
    • Cytoplasm; Cytosol; Secreted
    • Function
    • Potent pro-inflammatory cytokine.
      Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
      Promotes Th17 differentiation of T-cells.
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    Related Diseases

    Rheumatoid Arthritis Rheumatoid Arthritis
    Maturity Onset Diabetes of the Young Maturity Onset Diabetes of the Young

    Related Signaling Pathways

    TNF Signaling Pathway TNF Signaling Pathway

    Downloadable Resources

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Datasheet

    Datasheet - VS-0724-XY84.pdf

    MSDS

    MSDS - VS-0724-XY84.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

    Lot Number:

    Isotype Control

    • CAT
    • Product Name

    Recommended Dilution Buffer

    • CAT
    • Product Name

    Secondary Antibody

    • CAT
    • Product Name

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