Human Anti-IL1R1 Recombinant Antibody (clone 15C4) (CAT#: HPAB-1863-FY)
This product is a recombinant antibody that recognizes IL1R1. The monoclonal antibody 15C4 reacts with the epitope of IL1R1.
Specific Inquiry
Inhib
Figure 1 Shows a graph illustrating the inhibitory effect of anti-IL-1R1 antibodies on IL-1R/IL-13/IL-1RAcP complex formation.
Block
Figure 2 Shows a graph representing the ability of anti-IL-1R1 antibodies to block IL-1β binding while not significantly interfering with binding of IL-1ra compared with IgG control.
Inhib
Figure 3 Shows a graph showing inhibition of IL-6 production in primary human chondrocytes by anti-IL-1R1 antibodies identified herein and designated 15C4, 26F5, and 27F2 compared with IL-1ra.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human IL1R1
- Species Reactivity
- Human
- Clone
- 15C4
- Applications
- Inhib, Block
- Related Disease
- Rheumatoid arthritis, osteoarthritis, and other inflammatory conditions
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL1R1 antibody has been reported in applications of Inhibition, Blocking.
Target
Related Resources
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 15C4"
See other products for "IL1R1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1421z | Mouse Anti-IL1R1 Recombinant Antibody (clone 32H6) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| MOB-0953CT | Recombinant Mouse anti-Human IL1R1 Monoclonal antibody (732229) | ELISA, ICC/IF, RIA | |
| HPAB-1862-FY | Human Anti-IL1R1 Recombinant Antibody (clone 26F5) | Inhib, Block | Human IgG1 |
| VS3-QX596 | Mouse Anti-IL1R1 Recombinant Antibody (clone D12-D2) | WB, FC, ELISA | Mouse IgG1 |
| VS3-QX597 | Mouse Anti-IL1R1 Recombinant Antibody (clone 4D2D12) | ELISA, FC | Mouse IgG1 |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L026P | anti-IL1R1 immunotoxin TP3 (IgG)-PAP | Cytotoxicity assay, Functional assay |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-409CL | Human Anti-IL1R1 Recombinant Antibody (TAB-409CL) | FuncS | Human IgG |
| TAB-213CT-S(P) | Human Anti-IL1R1 Recombinant Antibody; scFv Fragment (TAB-213CT-S(P)) | ELISA, BL | Human scFv |
| TAB-214CT-S(P) | Human Anti-IL1R1 Recombinant Antibody; scFv Fragment (TAB-214CT-S(P)) | ELISA, BL | Human scFv |
| TAB-215CT-S(P) | Anti-Human IL-1R1 (interleukin-1 receptor 1) Recombinant Antibody scFv Fragment (6GL) | ELISA, BL | Human antibody |
| TAB-220CT-S(P) | Human Anti-IL1R1 Recombinant Antibody; scFv Fragment (TAB-220CT-S(P)) | ELISA, Inhibion, BL, IB | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-392CL | Afuco™ Anti-IL1R1 Recombinant Antibody (AFC-392CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-216CT | Anti-Human IL-1R1 (Interleukin 1 receptor type 1) Therapeutic Single Domain Antibody (DOM4-130) | Inhib | Single domain antibody |
| TAB-217CT | Anti-Human IL-1R1 (Interleukin 1 receptor type 1) Therapeutic Single Domain Antibody (D0M4-130-46) | ELISA | Single domain antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1293CQ | Hamster Anti-Il1r1 Recombinant Antibody (clone JAMA147) | Neut | Hamster IgG |
| NEUT-1294CQ | Rat Anti-Il1r1 Recombinant Antibody (clone CBL936) | ELISA, IP, Neut, WB | Rat IgG1 |
| NEUT-1295CQ | Rat Anti-Il1r1 Recombinant Antibody (clone CBL937) | Neut, WB | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1799 | Rabbit Anti-IL1R1 Recombinant Antibody (clone DS1799AB) | WB, FC, IP | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1862-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 26F5); scFv Fragment | ELISA | Human scFv |
| HPAB-1863-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 15C4); scFv Fragment | ELISA | Human scFv |
| HPAB-1864-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 27F2); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1862-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 26F5); Fab Fragment | ELISA | Human Fab |
| HPAB-1863-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 15C4); Fab Fragment | ELISA | Human Fab |
| HPAB-1864-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 27F2); Fab Fragment | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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